Most Read Articles
Roshini Claire Anthony, 3 days ago

The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
3 days ago
Serum 25-hydroxyvitamin D (25[OH]D) levels are significantly lower among patients with active uveitis than those with inactive uveitis and local population-based estimates, reports a study. In addition, vitamin D supplementation may help reduce uveitis activity, while sun exposure confers a beneficial effect to those with vitamin D deficiency.
2 days ago
The timing of direct oral anticoagulants (DOACs) administration, either within 3 days or ≥4 days of stroke onset, in patients with nonvalvular atrial fibrillation (AF) does not alter the risk of adverse outcomes such as stroke or systemic embolism, major bleeding, and death, as shown in a recent study.

Early oral antibiotic exposure poses no risk for lung function in kids

31 Oct 2019

In children who have a family history of allergic diseases, exposure to oral antibiotics in early postnatal life does not appear to imperil lung function, a study reports.

The study included 620 infants with a family history of allergy. Researchers obtained parent-report of childhood antibiotic use from birth to 2 years, including type and indication. Spirometry was performed at age 12 and 18 years, and results were converted as z-scores. Furthermore, the children were genotyped for glutathione S-transferase (GST) superfamily to assess whether genetic mutations were associated with a greater risk.

Linear regression analysis revealed that neither the number of days nor timing of exposure to antibiotics was associated with reduced forced expiratory volume in 1 second (at 18 years per doubling of days of exposure, –0.03 z-score units, 95 percent confidence interval [CI], –0.11 to 0.04) or forced vital capacity (<0.01, 95 percent CI, –0.08 to 0.07).

There was no evidence that GST-risk polymorphisms (M1, P1 and T1) contributed to increased susceptibility, nor did specific types of antibiotics increase the risk of lung function deficits.

The present data provide some reassurance that early antibiotic exposure does not exert a negative effect on long term lung health, according to the researchers. Therefore, while unwarranted use of antibiotics in children should be lessened, concerns for long term lung health should not be a driving influence for this rationalization of use.

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Most Read Articles
Roshini Claire Anthony, 3 days ago

The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
3 days ago
Serum 25-hydroxyvitamin D (25[OH]D) levels are significantly lower among patients with active uveitis than those with inactive uveitis and local population-based estimates, reports a study. In addition, vitamin D supplementation may help reduce uveitis activity, while sun exposure confers a beneficial effect to those with vitamin D deficiency.
2 days ago
The timing of direct oral anticoagulants (DOACs) administration, either within 3 days or ≥4 days of stroke onset, in patients with nonvalvular atrial fibrillation (AF) does not alter the risk of adverse outcomes such as stroke or systemic embolism, major bleeding, and death, as shown in a recent study.