Most Read Articles
Pearl Toh, 5 days ago
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
4 days ago
Patients with psoriatic arthritis (PsA) often suffer from liver abnormalities, which are associated with higher body mass index (BMI), daily consumption of alcohol, more severe disease, and some therapies, according to a recent study.
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Pembrolizumab in combination with chemotherapy significantly improves progression-free survival (PFS) vs chemotherapy alone in patients with previously untreated, locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC), results of the KEYNOTE-355 study have shown.

Pearl Toh, 25 Jun 2020
The type of face mask matters, in addition to sterilization method, in influencing subsequent filtration efficiency after sterilization process for reuse, a new study finds.

Early-onset nephrolithiasis tied to frequent stone recurrences

20 Apr 2020

Individuals who develop stones prior to age 20 years are at high risk of having frequent recurrences, with the risk even more pronounced in women, a study has found.

The analysis included 1,140 patients enrolled in the Registry for Stones of the Kidney and Ureter (ReSKU). Researchers collected data on patient age, gender, body mass index (BMI), family history, race, income, infectious symptoms and number of prior stone episodes. None of the patients had a history of cystinuria stones.

A total of 472 patients had recurrent stones, among whom 66 had their first episode prior to the age of 20 years. Univariate analysis showed that early stone formers were more likely to present at a younger age, be female and have more prior stone episodes at baseline.

Analysis controlled for potential confounders confirmed that early-onset nephrolithiasis was associated with female gender and frequent stone episodes. On the other hand, late stone formers were more likely to have greater BMI (>30 kg/m2).

The present data underscore the importance of close follow-up and surveillance of early stone formers due to the increased rate of recurrence, the researchers said, noting that adult stone databases focusing on early presentations may help improve understanding of paediatric stone disease.

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Most Read Articles
Pearl Toh, 5 days ago
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
4 days ago
Patients with psoriatic arthritis (PsA) often suffer from liver abnormalities, which are associated with higher body mass index (BMI), daily consumption of alcohol, more severe disease, and some therapies, according to a recent study.
Christina Lau, 3 days ago

Pembrolizumab in combination with chemotherapy significantly improves progression-free survival (PFS) vs chemotherapy alone in patients with previously untreated, locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC), results of the KEYNOTE-355 study have shown.

Pearl Toh, 25 Jun 2020
The type of face mask matters, in addition to sterilization method, in influencing subsequent filtration efficiency after sterilization process for reuse, a new study finds.