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4 days ago
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Jairia Dela Cruz, 4 days ago
Following vegan and vegetarian diets, which offer plenty of what is good for health, has been reported to have a downside: an increased risk of depression and anxiety, especially for younger adults.
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Upadacitinib may be a suitable treatment for patients with active psoriatic arthritis (PsA) who have insufficient response to non-biologic disease-modifying anti-rheumatic drugs (non-bDMARDs), according to results of the phase III SELECT-PsA-1* trial presented at EULAR 2020.

Early-onset nephrolithiasis tied to frequent stone recurrences

20 Apr 2020

Individuals who develop stones prior to age 20 years are at high risk of having frequent recurrences, with the risk even more pronounced in women, a study has found.

The analysis included 1,140 patients enrolled in the Registry for Stones of the Kidney and Ureter (ReSKU). Researchers collected data on patient age, gender, body mass index (BMI), family history, race, income, infectious symptoms and number of prior stone episodes. None of the patients had a history of cystinuria stones.

A total of 472 patients had recurrent stones, among whom 66 had their first episode prior to the age of 20 years. Univariate analysis showed that early stone formers were more likely to present at a younger age, be female and have more prior stone episodes at baseline.

Analysis controlled for potential confounders confirmed that early-onset nephrolithiasis was associated with female gender and frequent stone episodes. On the other hand, late stone formers were more likely to have greater BMI (>30 kg/m2).

The present data underscore the importance of close follow-up and surveillance of early stone formers due to the increased rate of recurrence, the researchers said, noting that adult stone databases focusing on early presentations may help improve understanding of paediatric stone disease.

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Most Read Articles
4 days ago
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Jairia Dela Cruz, 4 days ago
Following vegan and vegetarian diets, which offer plenty of what is good for health, has been reported to have a downside: an increased risk of depression and anxiety, especially for younger adults.
Pearl Toh, 29 Jun 2020
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
Roshini Claire Anthony, 2 days ago

Upadacitinib may be a suitable treatment for patients with active psoriatic arthritis (PsA) who have insufficient response to non-biologic disease-modifying anti-rheumatic drugs (non-bDMARDs), according to results of the phase III SELECT-PsA-1* trial presented at EULAR 2020.