Most Read Articles
26 Jun 2020

Achieving standard of care targets, such as reduced levels of low-density lipoprotein cholesterol and glycated haemoglobin, improves outcomes in coronary heart disease patients, a new study has found.

Pearl Toh, 19 Jan 2018
Blood pressure (BP) control can be best achieved with a multilevel, multicomponent approach involving team-based care with physician- and non-physician-led interventions, as well as patient-level strategies, according to findings of a meta-analysis.
Dr. Joseph Delano Fule Robles, 24 Jul 2018

Functional foods benefit the body beyond its nutritional effects, with studies showing that they can improve general state of health and reduce the risk of diseases.

29 Mar 2020
Targeting a low-density lipoprotein cholesterol level <70 mg/dL following an ischaemic stroke of atherosclerotic origin helps to avoid one in four subsequent major vascular events without increasing the risk of intracranial haemorrhage over about 5 years of follow-up, according to data from the Treat Stroke to Target trial.

Early-onset hypertension tied to greater CVD, mortality risks

15 Jun 2020

Hypertension appears to increase the risk of cardiovascular disease (CVD) and all-cause mortality, with the risk being higher with a younger age of onset, suggests a recent study.

The investigators identified 1,672 incident CVD cases and 2,008 deaths over a mean follow-up of 6.5 years. Outcome hazards gradually attenuated with the increase in hypertension onset age after multivariate adjustment.

The average hazard ratios (HRs) of CVD and all-cause mortality were as follows: 2.26 (95 percent confidence interval [CI], 1.19–4.30) and 2.59 (95 percent CI, 1.32–5.07) for the hypertension onset age <45 years old group; 1.62 (95 percent CI, 1.24–2.12) and 2.12 (95 percent CI, 1.55–2.90) for the 45- to 54-year age group; 1.42 (95 percent CI, 1.12–1.79) and 1.30 (95 percent CI, 1.03–1.62) for the 55- to 64-year age group; and 1.33 (95 percent CI, 1.04–1.69) and 1.29 (95 percent CI, 1.11–1.51) for the ≥65-year age group, respectively (pinteraction=0.38 for CVD; p<0.01 for death).

This study included 71,245 participants free of hypertension and CVD in the first survey (July 2006 to October 2007) of the Kailuan study, a prospective cohort study in Tangshan, China. Participants were followed biennially until 31 December 2017. During follow-up, a total of 20,221 new-onset hypertension cases were identified. One control participant was randomly selected for each new-onset hypertensive individual, matching for age and sex. Overall, 19,887 case-control pairs were included.

Weighted Cox regression models were used to calculate the average HRs of incident CVD and all-cause mortality across the age groups.

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Most Read Articles
26 Jun 2020

Achieving standard of care targets, such as reduced levels of low-density lipoprotein cholesterol and glycated haemoglobin, improves outcomes in coronary heart disease patients, a new study has found.

Pearl Toh, 19 Jan 2018
Blood pressure (BP) control can be best achieved with a multilevel, multicomponent approach involving team-based care with physician- and non-physician-led interventions, as well as patient-level strategies, according to findings of a meta-analysis.
Dr. Joseph Delano Fule Robles, 24 Jul 2018

Functional foods benefit the body beyond its nutritional effects, with studies showing that they can improve general state of health and reduce the risk of diseases.

29 Mar 2020
Targeting a low-density lipoprotein cholesterol level <70 mg/dL following an ischaemic stroke of atherosclerotic origin helps to avoid one in four subsequent major vascular events without increasing the risk of intracranial haemorrhage over about 5 years of follow-up, according to data from the Treat Stroke to Target trial.