Most Read Articles
21 Feb 2021
The efficacy and safety of the two-bag (TB) system are comparable to those of the one-bag (OB) system in adults with diabetic ketoacidosis (DKA), results of a study have shown. Both approaches can be considered in adult DKA patients.
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
05 Feb 2021

Primary immunodeficiency disease (PIDD) and allergies are two groups of conditions related to the immune system. However, they are uniquely different in terms of symptoms and treatment.

Early life exposure helps ward off later allergies to cow’s milk formula

17 Jan 2021

Daily intake of cow’s milk formula (CMF) in early life helps prevent the development of cow’s milk allergy (CMA) later on without competing with breastfeeding, a recent study has found.

The researchers conducted a randomized controlled trial, testing daily CMF ingestion (n=242) against avoidance (n=249). Infants between the ages of 1 and 2 months were enrolled into the trial and continued regular breastfeeding. CMA was assessed at 6 months of age via an oral food challenge (OFC).

Adherence to the intervention was high, with 89.9 percent of the CMF group ingesting the milk formula for at least 20 days per month. In the avoidance group, 83.0 percent were able to abstain from CMF for at least 20 days per month. The proportion of participants with daily CMF intake between 3 and 5 months of age was significantly higher in the ingestion group (p<0.001).

At 6 months of age, OFC-confirmed CMA was detected in 0.8 percent of the intervention group and 6.8 percent of the avoidance group, in the intention-to-treat population. Infants who were given CMF saw a significant reduction in CMA risk (risk ratio [RR], 0.12, 95 percent confidence interval [CI], 0.01–0.05; p<0.001).

Results were better in the per-protocol analysis, where none of the ingestion participants tested positive for CMA, as opposed to 8.7 percent of the avoidance group (p<0.001).

The intervention safe, with no CMF-related adverse events recorded throughout the course of the study. Twenty patients, all in the avoidance group, developed transient gastrointestinal symptoms following the intake of soy formula. Overall, 30 participants had to withdraw from the study, though none were due to the trial formulas.

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Most Read Articles
21 Feb 2021
The efficacy and safety of the two-bag (TB) system are comparable to those of the one-bag (OB) system in adults with diabetic ketoacidosis (DKA), results of a study have shown. Both approaches can be considered in adult DKA patients.
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
05 Feb 2021

Primary immunodeficiency disease (PIDD) and allergies are two groups of conditions related to the immune system. However, they are uniquely different in terms of symptoms and treatment.