Most Read Articles
12 Jun 2018
Percutaneous coronary intervention (PCI) is a safe procedure to perform on obese and morbidly obese patients, a recent study has shown.
Roshini Claire Anthony, 11 Jun 2018

Patients who received a combination of ticagrelor plus aspirin within 24 hours of undergoing coronary artery bypass grafting (CABG) had significantly improved saphenous vein graft patency rates 1 year post-procedure compared with those who only received aspirin, according to findings of the DACAB* trial.

4 days ago
Higher activity of plasma xanthine oxidase appears to be linked to insulin resistance and liver dysfunction among type 2 diabetes mellitus (T2DM) patients with metabolic syndrome (MetS), according to a recent Japan study.
4 days ago
Use of quetiapine among critically ill patients rarely leads to corrected QT (QTc) interval prolongation, reports a new study.

E-cigarettes may help smokers quit

03 Jan 2018
Vaping can help cut rates of smoking, says Reason Foundation think tank

Electronic nicotine delivery systems (ENDS) appear to aid in smoking cessation, a recent randomized naturalistic trial has shown.

The study included 68 adult smokers with minimal ENDS experience who were randomized to receive 16 mg of ENDS (n=25), 24 mg of ENDS (n=21), or no ENDS (n=22). Upon trial initiation, cigarettes per day (CPD) dropped, particularly for the 16-mg (mean 8.4 CPD) and 24-mg (mean 5.3 CPD) groups. In comparison, control participants averaged 11.2 CPD. The trial lasted for 3 weeks.

During the 21-day trial period, cigarette consumption of the participants who received the 16-mg and 24-mg ENDS decreased by 30.2 and 45.1 percent, respectively, while consumption of the control group increased by 0.7 percent.

By the end of the trial period, 35 and 30 percent of the 24-mg and 16-mg ENDS groups, respectively, reduced their smoking by at least half from baseline levels. Only 5 percent of the control group reached this level of smoking reduction (p=0.07 overall).

The motivation to quit was also significantly higher in ENDS participants, regardless of dose, than in controls (p=0.05 overall).

While none of the cessation-related behaviours were significantly more apparent in any particular group, the incidence rates of 24-hour quit attempts (odds ratio [OR], 3.1; 95 percent CI, 0.8–11.5) and floating abstinence (OR, 6.7; 0.7–61.9) showed positive trends in favour of ENDS participants.

The current study shows that in a real-world setting, there is a strong interest in ENDS among smokers, and that use of the technology may help in smoking cessation.

ENDS technology, which includes e-cigarettes and vaping devices, has attracted much attention because of its potential in helping with smoking cessation. However, there have been some inconsistencies in the literature, and the existing studies are limited either by self-selected samples or unrealistic e-cigarette prescriptions. [Addict Behav 2014;39:491-494; Am J Public Health 2017;105:1213-1219]

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
12 Jun 2018
Percutaneous coronary intervention (PCI) is a safe procedure to perform on obese and morbidly obese patients, a recent study has shown.
Roshini Claire Anthony, 11 Jun 2018

Patients who received a combination of ticagrelor plus aspirin within 24 hours of undergoing coronary artery bypass grafting (CABG) had significantly improved saphenous vein graft patency rates 1 year post-procedure compared with those who only received aspirin, according to findings of the DACAB* trial.

4 days ago
Higher activity of plasma xanthine oxidase appears to be linked to insulin resistance and liver dysfunction among type 2 diabetes mellitus (T2DM) patients with metabolic syndrome (MetS), according to a recent Japan study.
4 days ago
Use of quetiapine among critically ill patients rarely leads to corrected QT (QTc) interval prolongation, reports a new study.