Most Read Articles
13 Mar 2017
The serum pepsinogen test—which is relatively simple, inexpensive, sensitive and specific—is a potentially viable method for the screening and detection of Kazakh early gastric cancer, a new study claims.
24 Apr 2017

Helicobacter pylori (H. pylori) infection is associated with conditions such as gastritis, peptic ulcer, gastric cancer, and certain types of lymphoma. A common presenting complaint among all these H. pylori-related illnesses is dyspepsia. Dr Desmond Wai from the Desmond Wai Liver and Gastrointestinal Diseases Centre, Mount Elizabeth Novena Specialist Centre, Singapore, speaks on the important role general practitioners (GPs) play in recognizing, diagnosing, and treating H. pylori.

Pearl Toh, 24 Nov 2016
New treatments such as pirfenidone and nintedanib slow lung function decline and progression of idiopathic pulmonary fibrosis (IPF), although response to treatment can vary dramatically among patients, according to a presentation at the 21st Congress of the Asian Pacific Society of Respirology (APSR 2016) held in Bangkok, Thailand.
Clare Cuckson, 01 Jun 2012
During pregnancy, there is generalized relaxation of smooth muscle resulting in relaxa¬tion of the oesophageal sphincter, reduced gastric peristalsis, and delayed gastric emp¬tying. Small and large bowel transit times are increased. There is increased blood flow to the liver and increased production of fibrinogen, transferrin and many other binding proteins. Reference ranges for many liver function tests are altered. Gestation-specific alkaline phosphatase is increased, mainly from increased placental production, and aminotransferases and γ-glutamyltransferase are reduced.

 

Donor-patient compatibility may play important role in stool transplant

12 May 2016

A study published in Science shows new strains of microbes from the donor were more likely to colonize the patient’s intestines if that particular species exists in the patient’s gut.

The finding suggests that by matching donors to patients, the success of faecal microbiota transplant can be considerably increased. Moreover, focusing on bacterial strands instead of species could also improve the effectiveness of the novel therapy in conditions where it’s currently not effective.

The bulk of the population has Escherichia coli in their intestines but different people have different strains of the species; some strains can cause health issues. By differentiating between the strains, the researchers could track if the microbes in a patient’s gut after a stool transplant were their own or came from the donor.

Using this approach we can examine if, for instance, an antibiotic-resistant strain is replaced by a non-resistant one, said lead researcher Professor Willem de Vos, of the Wageningen University, Netherlands. It could then aid in designing stool transplants for other conditions besides recurrent Clostridium difficile infections.

The study is part of a clinical trial on the use of stool transplants as a treatment modality for metabolic syndrome. The data is collected from only 10 participants but there are strong indications that donor-patient compatibility plays a bigger role than previously thought; transplants from one donor led to very different outcomes in three individual patients.

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Most Read Articles
13 Mar 2017
The serum pepsinogen test—which is relatively simple, inexpensive, sensitive and specific—is a potentially viable method for the screening and detection of Kazakh early gastric cancer, a new study claims.
24 Apr 2017

Helicobacter pylori (H. pylori) infection is associated with conditions such as gastritis, peptic ulcer, gastric cancer, and certain types of lymphoma. A common presenting complaint among all these H. pylori-related illnesses is dyspepsia. Dr Desmond Wai from the Desmond Wai Liver and Gastrointestinal Diseases Centre, Mount Elizabeth Novena Specialist Centre, Singapore, speaks on the important role general practitioners (GPs) play in recognizing, diagnosing, and treating H. pylori.

Pearl Toh, 24 Nov 2016
New treatments such as pirfenidone and nintedanib slow lung function decline and progression of idiopathic pulmonary fibrosis (IPF), although response to treatment can vary dramatically among patients, according to a presentation at the 21st Congress of the Asian Pacific Society of Respirology (APSR 2016) held in Bangkok, Thailand.
Clare Cuckson, 01 Jun 2012
During pregnancy, there is generalized relaxation of smooth muscle resulting in relaxa¬tion of the oesophageal sphincter, reduced gastric peristalsis, and delayed gastric emp¬tying. Small and large bowel transit times are increased. There is increased blood flow to the liver and increased production of fibrinogen, transferrin and many other binding proteins. Reference ranges for many liver function tests are altered. Gestation-specific alkaline phosphatase is increased, mainly from increased placental production, and aminotransferases and γ-glutamyltransferase are reduced.