Most Read Articles
Elaine Soliven, 5 days ago

Switching from efavirenz/emtricitabine/tenofovir disoproxil fumarate (EFV/FTC/TDF) to the new bictegravir/ emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) regimen maintained high rates of virological suppression in adults who are living with HIV*, according to a study presented at AIDS 2020.

3 days ago
Among individuals with abdominal obesity, drinking beverages with artificial sweeteners (ASBs) or no sugar (USBs) instead of sugar-sweetened beverages (SSBs) helps lose body weight, a study has found. However, USBs have a more favourable effect on sweet taste preference compared with ASBs.
Stephen Padilla, 5 days ago
Pre-exposure prophylaxis (PrEP) containing either long-acting injectable cabotegravir (CAB) or tenofovir/emtricitabine (TDF/FTC) is safe and effective for transgender women (TGW) and cisgender men who have sex with men (MSM), but CAB results in a much lower HIV incidence compared to TDF/FTC, results of the HIV Prevention Trials Network (HPTN) 083 have shown.
Jairia Dela Cruz, 4 days ago
Monthly prophylaxis with the fixed-dose combination of naphthoquine-azithromycin (NQAZ) is well tolerated and confers significant protection against infection with Plasmodium parasites among individuals residing in malaria-endemic areas in Southeast Asia, as shown in the results of a phase III trial.

Distance travelled affects time to surgery in kids with focal cortical dysplasia

02 Jun 2020

Sociodemographic factors appear to be important determinants of time to epilepsy surgery for children with focal cortical dysplasia (FCD), a new study has shown.

Researchers conducted a retrospective review of 94 consecutive paediatric patients (median age at seizure onset, 3.0 years) with FCD who underwent surgery for epilepsy. Factors assessed included seizure history, preoperative imaging, travel distance, and health insurance, among others. Postsurgical outcomes were evaluated using the Engel Epilepsy Surgery Outcome Scale.

The average follow-up after surgery was 24 months, during which time 58 of the participant underwent neuropsychological evaluation with IQ testing. Most of the participants resided within the state where the medical centre was located, while 20 had to travel from out of state. Majority (73 percent) had private insurance, while 21 percent were government-insured. Five percent were uninsured.

Patients were then grouped according to distance travelled to hospital. For those within the same state, the median distance was 30.7 miles. Those who travelled below the median distance tended to be older (p=0.005) and had a longer duration of epilepsy prior to the operation (p=0.01). These patients were also more likely to have focal to bilateral tonic-clonic seizures than their out-of-state counterparts (p=0.04).

Moreover, the median number of failed antiseizure medications was significantly lower in those who travelled within the state (below the median distance: 2.00±2.14; above the median distance: 2.00±1.61; out-of-state: 3.00±2.37; p=0.06).

However, univariate and multivariate analyses did not find distance travelled, health insurance, and other demographic factors to be significantly predictive of seizure control after surgery.

“Further research is warranted to target barriers in access to subspecialty care and develop programs to identify earlier the patients who may benefit from workup and deployment of surgical intervention,” said researchers.

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Most Read Articles
Elaine Soliven, 5 days ago

Switching from efavirenz/emtricitabine/tenofovir disoproxil fumarate (EFV/FTC/TDF) to the new bictegravir/ emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) regimen maintained high rates of virological suppression in adults who are living with HIV*, according to a study presented at AIDS 2020.

3 days ago
Among individuals with abdominal obesity, drinking beverages with artificial sweeteners (ASBs) or no sugar (USBs) instead of sugar-sweetened beverages (SSBs) helps lose body weight, a study has found. However, USBs have a more favourable effect on sweet taste preference compared with ASBs.
Stephen Padilla, 5 days ago
Pre-exposure prophylaxis (PrEP) containing either long-acting injectable cabotegravir (CAB) or tenofovir/emtricitabine (TDF/FTC) is safe and effective for transgender women (TGW) and cisgender men who have sex with men (MSM), but CAB results in a much lower HIV incidence compared to TDF/FTC, results of the HIV Prevention Trials Network (HPTN) 083 have shown.
Jairia Dela Cruz, 4 days ago
Monthly prophylaxis with the fixed-dose combination of naphthoquine-azithromycin (NQAZ) is well tolerated and confers significant protection against infection with Plasmodium parasites among individuals residing in malaria-endemic areas in Southeast Asia, as shown in the results of a phase III trial.