Most Read Articles
Pearl Toh, 5 days ago
A latest study at ISC 2019 shows that even patients with large-core stroke damage can have a good outcome after mechanical clot removal with endovascular thrombectomy (EVT), depending on the size of the infarct and time lapses between stroke onset and treatment.
30 Nov 2018
Poor adherence to statin therapy is leaving many patients with dyslipidaemia at high risk of potentially life-threatening cardiovascular events. Statins are the current standard of care for reducing the risk of cardiovascular disease in these patients and for improving life expectancy, with possible economic benefits for healthcare systems too. However, many patients with dyslipidaemia are not achieving or maintaining treatment targets because they fail to stick to their prescribed statin therapy. An article co-authored by lipidologist Peter Lansberg, and published in Vascular Health and Risk Management, considers this issue and reviews approaches to overcome non-adherence.

Diets rich in cottonseed oil improve fasting cholesterol, triglyceride

08 Nov 2018
Used cooking oil must be stored properly for safe re-use.

A high-fat diet rich in cottonseed oil (CSO) appears to effectively improve cholesterol and triglyceride concentrations, a recent study has found. In contrast, olive oil (OO)-rich diets exert no such effects.

Researchers randomly assigned 15 normal-weight men (mean age 21.6±2.58 years; mean body mass index, 24.27±2.81 kg/m2) to receive either CSO-rich or OO-rich diets for 5 days before crossover. Diets were 50-percent fat and blood samples were collected during pre- and postdiet visits.

Fasting levels of total cholesterol dropped from previsit values following the CSO diet (148.40±6.39 to 135.93±6.31 mg/dL; p<0.05). No such effect was observed during the OO-intervention arm (149.71±6.38 vs 140.93±6.92 mg/dL).

Similar effects on fasting low-density lipoprotein cholesterol (LDL-C) levels were observed for the CSO (92.20±5.57 to 78.13±5.60 mg/dL; p<0.05) and OO (91.14±6.87 to 85.64±6.29 mg/dL) interventions. The same was true for fasting triglyceride levels (CSO: 80.11±4.91 to 56.37±5.46 mg/dL; p<0.05; OO: 74.51±8.38 to 64.08±6.87 mg/dL).

In contrast, the CSO diet led to significant increases in the mean fasting high-density lipoprotein cholesterol (HDL-C) levels (46.67±2.41 to 50.24±2.20 mg/dL; p<0.05), while the OO diet remained ineffective (48.92±2.44 to 48.21±1.92 mg/dL).

In terms of between-diet comparisons, researchers found that LDL-C (78.13±5.61 vs 85.64±6.29 mg/dL; p<0.05) and triglyceride (56.37±5.46 vs 64.08± 6.87 mg/dL; p<0.05) concentrations were significantly lower following the CSO vs OO diets.

The present findings underline the value of CSO in improving fasting lipid profiles and its potential in reducing the risk of conditions such as obesity, type 2 diabetes and nonalcoholic fatty liver disease, said researchers.

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Most Read Articles
Pearl Toh, 5 days ago
A latest study at ISC 2019 shows that even patients with large-core stroke damage can have a good outcome after mechanical clot removal with endovascular thrombectomy (EVT), depending on the size of the infarct and time lapses between stroke onset and treatment.
30 Nov 2018
Poor adherence to statin therapy is leaving many patients with dyslipidaemia at high risk of potentially life-threatening cardiovascular events. Statins are the current standard of care for reducing the risk of cardiovascular disease in these patients and for improving life expectancy, with possible economic benefits for healthcare systems too. However, many patients with dyslipidaemia are not achieving or maintaining treatment targets because they fail to stick to their prescribed statin therapy. An article co-authored by lipidologist Peter Lansberg, and published in Vascular Health and Risk Management, considers this issue and reviews approaches to overcome non-adherence.