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Pearl Toh, 3 days ago
The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
Audrey Abella, 5 days ago
Extremes of sleep duration (≤5 or ≥10 hours/day), which is a known mortality risk factor in the general population, may increase absolute mortality in adults with type 2 diabetes (T2D), a prospective study has shown.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
Roshini Claire Anthony, 12 Oct 2020

Insulin icodec, an in-development basal insulin analogue administered once weekly, was as effective as once-daily insulin glargine in patients with type 2 diabetes (T2D) insufficiently controlled with metformin with or without a DPP-4* inhibitor, according to a phase II trial presented at EASD 2020.

Dietary diversity may help prolong life

22 Jan 2020

Eating a variety of foods, particularly fruits and soy products, is associated with a lower risk of mortality, suggests a Japan study.

Total dietary diversity was inversely associated with mortality rates in women (highest quintile hazard ratio [HR], 0.81, 95 percent confidence interval [CI], 0.71–0.92; p-trend=0.002), but the same trend was not found in men (highest quintile HR, 0.96, 95 percent CI, 0.87–1.10; p-trend=0.266).

Fruit diversity was likewise associated with lower mortality rates in men (highest quintile HR, 0.87, 95 percent CI, 0.79–0.95; p-trend=0.006), while soy diversity correlated with lower mortality rates in women (highest quintile HR, 0.89, 95 percent CI, 0.79–1.00; p-trend=0.004).

On the other hand, meat (highest quintile diversity HR, 1.15, 95 percent CI, 1.06–1.25) and fish diversity (highest quintile diversity HR, 1.12, 95 percent CI, 1.02–1.22) correlated with higher mortality rates in men.

“These findings indicate that consuming a greater diversity of total foods and increasing the diversity of fruit and soy consumed have considerable public health implications,” the authors said.

This study followed a total of 79,904 participants (37,240 men and 42,664 women) aged 45–74 years, without histories of ischaemic heart disease, stroke or cancer, for a median of 14.9 years (from 1995–2012). The authors used 133 food and beverage items listed on a 5-year follow-up food frequency questionnaire and counted the daily frequency of consumption for each item (excluding five alcoholic beverages).

HRs and corresponding 95 percent CIs were calculated using multivariable-adjusted Cox proportional hazards regression models to compare the highest and lowest quintiles.

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Most Read Articles
Pearl Toh, 3 days ago
The combination therapy comprising carfilzomib, cyclophosphamide and dexamethasone (KCd) is effective, with a tolerable safety profile, in an Asian cohort with high-risk multiple myeloma (MM) — thus providing a more economical alternative as a potential upfront regimen in resource-limited settings, according to leading experts during a myeloma education webinar.
Audrey Abella, 5 days ago
Extremes of sleep duration (≤5 or ≥10 hours/day), which is a known mortality risk factor in the general population, may increase absolute mortality in adults with type 2 diabetes (T2D), a prospective study has shown.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
Roshini Claire Anthony, 12 Oct 2020

Insulin icodec, an in-development basal insulin analogue administered once weekly, was as effective as once-daily insulin glargine in patients with type 2 diabetes (T2D) insufficiently controlled with metformin with or without a DPP-4* inhibitor, according to a phase II trial presented at EASD 2020.