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05 Aug 2018
In the treatment of proliferative diabetic retinopathy (DR), eyes gain vision and rarely develop vision-impairing central-involved diabetic macula oedema (DME) over 2 years with ranibizumab, according to a posthoc analysis. In contrast, factors such as poor glycaemic control and more severe DR increase the likelihood of losing visual acuity and developing DME following panretinal photocoagulation (PRP).

Diabetes mellitus ups risk of vision impairment in elderly adults

27 Apr 2018

Community-dwelling elderly adults with diabetes mellitus have a higher risk of near vision impairment (VI), particularly those with low or normal body mass index (BMI), a recent study has shown.

Over the 7-year study duration, 1,218 incident cases of near VI were reported. Both diagnosed and undiagnosed DM were associated with significantly elevated risks of near VI development (hazard ratio [HR], 1.29; 95 percent CI, 1.07–1.56).

While this relationship was attenuated following full adjustments for age, sex, health behaviours, hearing impairment, among other covariates (HR, 1.19; 0.98–1.43; p=0.07), the association remained significant when only diagnosed DM was considered (HR, 1.24; 1.02–1.52) in the fully adjusted model.

However, when frailty was taken into consideration, DM, whether undiagnosed (HR, 1.23; 0.98–1.54; p=0.07) or diagnosed (HR, 1.24; 0.98–1.59; p=0.08) was not significantly associated with near VI development.

Further analyses showed that body mass index (BMI) may also have a role to play in this association. Fully adjusted Cox models showed that participants with DM and who were also underweight (hazard ratio [HR], 2.89; p=0.02) and normal-weight (HR, 1.60; p=0.01) had a significantly higher risk of VI development.

“Because near vision is required to perform almost all [activities of daily living], older people with DM need special monitoring by an ophthalmologist, not only for a dilated eye examination, but also to assess their global visual function and treat any correctable impairments,” said researchers.

For the longitudinal study, researchers recruited 8,412 community-dwelling elderly adults (aged 65 years), of whom 690 had diagnosed DM while 117 had undiagnosed DM. Near VI was defined as having a Snellen score greater than 20/30.

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Most Read Articles
05 Aug 2018
In the treatment of proliferative diabetic retinopathy (DR), eyes gain vision and rarely develop vision-impairing central-involved diabetic macula oedema (DME) over 2 years with ranibizumab, according to a posthoc analysis. In contrast, factors such as poor glycaemic control and more severe DR increase the likelihood of losing visual acuity and developing DME following panretinal photocoagulation (PRP).