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20 Apr 2018
Among patients with rheumatoid arthritis, those who are obese are more likely to have worse disease activity, lower functional ability and poorer health-related quality of life compared with their nonobese counterparts, a study has found.
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The high-concentration capsaicin patch shows promise in the management of painful diabetic peripheral neuropathy (PDPN), with an effect that is similar to that observed with oral agents but offering systemic tolerability benefits, according to a network meta-analysis.

Diabetes mellitus ups risk of hospital-acquired infections in burn injury patients

09 Mar 2018

In patients admitted for burn injuries, diabetes mellitus (DM) significantly increases the risk of hospital-acquired infections (HAI) but does not seem to affect the risk of mortality, a recent study has shown.

The study included 5,539 adult patients who were admitted to a hospital for burn injuries and whose records were accessed to identify DM cases. Kaplan-Meier survival curves were used to determine the risk of 30- and 60-day mortality and HAIs.

The percentage of participants who were diagnosed with DM was 11.8 percent (n=655), which grew significantly over time (p=0.01). Contact burns (8.9 percent vs 4.7 percent; p0.0001) and inhalational injuries (11.0 percent vs 8.1 percent; p=0.01) were significantly more common in diabetics vs nondiabetics.

There were 4,426 patients (79.9 percent) who were hospitalized for at least 2 days and were at risk of infection, of whom 8.5 percent (n=378) developed at least one HAI. Significantly more diabetic patients developed at least one HAI (9.9 percent vs 6.4 percent; p=0.0008), but the overall number of infections was statistically similar between the two patient groups (p=0.96).

After adjusting for hospitalization length and other potential confounders, patients with DM were significantly more likely to get an HAI vs those without DM (risk ratio, 2.07; 95 percent CI, 1.28–6.79).

In contrast, even after complete adjustments, 30- and 60-day mortality rates were comparable between burn patients with and without DM. The risks of mortality after 30 and 60 days were similar between patient groups. There were 243 in-hospital deaths recorded.

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Most Read Articles
20 Apr 2018
Among patients with rheumatoid arthritis, those who are obese are more likely to have worse disease activity, lower functional ability and poorer health-related quality of life compared with their nonobese counterparts, a study has found.
17 May 2017
The high-concentration capsaicin patch shows promise in the management of painful diabetic peripheral neuropathy (PDPN), with an effect that is similar to that observed with oral agents but offering systemic tolerability benefits, according to a network meta-analysis.