Most Read Articles
Elvira Manzano, 2 days ago
Monthly injections of the PCSK9* monoclonal antibody evolocumab effectively reduced plasma LDL-cholesterol (LDL-C), often referred to as the bad cholesterol, in teenagers with heterozygous familial hypercholesterolaemia (HeFH) already taking statins, with or without ezetimibe, the HAUSER-RCT has shown.
Jairia Dela Cruz, 2 days ago
For individual with type 2 diabetes, losing weight is everything when it comes to improving the metabolic function, and it matters little whether this is achieved by dieting or undergoing bariatric surgery, according to a small study.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
2 days ago
In patients with type 2 diabetes (T2D), postprandial hyperglycaemia and hypertriglyceridemia worsens survival outlook, finds a new study.

Desmoid tumour patients suffer from high emotional distress

04 Jan 2020

The burden of emotional distress is high among adults with desmoid tumours (DT), particularly in women and in patients with a history of mood problems, a new study reports.

Researchers enrolled 94 DT patients (mean age, 40 years; 78 percent female) who completed the Distress Assessment and Response Tool (DART) at four distinct time points: at diagnosis (T1), during treatment (T2) and at <6 (T3) and 6 (T4) months after treatment. DART scores also reported physical symptoms, depression, anxiety and social difficulties.

A total of 152 DART screens were included in the analysis. Almost half of the DT cases were located in the abdominal wall (48 percent); the extremities (30 percent) and mesentery (22 percent) were also common sites.

Significant longitudinal changes were reported for the patient symptoms of appetite (p=0.02), drowsiness (p=0.04) and tiredness (p=0.01), which peaked during treatment and decreased thereafter. The proportion of patients who were of poor wellbeing was consistently high across all time points (T1: 36 percent; T2: 45 percent; T3: 50 percent; T4: 31 percent; p=0.47).

The prevalence of moderate-to-severe levels of emotional distress likewise remained relatively stable at all time points, such that rates of anxiety ranged from 34 percent at T1 to 20 percent at T4 (p=0.44). The same was true for depression (T1: 25 percent; T2: 29 percent; T3: 27 percent; T4: 13 percent; p=0.63).

Multivariable regression analysis found that DT located at the abdominal wall was a significant predictor of distress, as were being a woman, having a personal history of mood problems, having difficulty with treatment decisions and problems with information about available resources.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Elvira Manzano, 2 days ago
Monthly injections of the PCSK9* monoclonal antibody evolocumab effectively reduced plasma LDL-cholesterol (LDL-C), often referred to as the bad cholesterol, in teenagers with heterozygous familial hypercholesterolaemia (HeFH) already taking statins, with or without ezetimibe, the HAUSER-RCT has shown.
Jairia Dela Cruz, 2 days ago
For individual with type 2 diabetes, losing weight is everything when it comes to improving the metabolic function, and it matters little whether this is achieved by dieting or undergoing bariatric surgery, according to a small study.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
2 days ago
In patients with type 2 diabetes (T2D), postprandial hyperglycaemia and hypertriglyceridemia worsens survival outlook, finds a new study.