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Depression tied to work, school absenteeism in patients with chronic constipation

20 Apr 2018
Men suffering from poor mental health may engage in self-harm or display suicidal thoughts or actions.

Depression appears to be a stronger predictor of absenteeism than symptom severity in patients with chronic constipation, suggests a study, adding that depression may partly contribute to the indirect costs of chronic constipation.

Of the 148 consecutive patients (mean age 43 years; 87 percent female) enrolled in the study, 32 (21.6 percent) had high absenteeism and 36 (24.3 percent) visited the emergency department (ED) for constipation in the past year. Depression was likely in patients with high absenteeism (56.3 percent vs 18.5 percent; p<0.0001) and ED visits (47.2 percent vs 19.6 percent; p<0.01).

Multivariable adjustment and sensitivity analyses revealed that only depression (odds ratio [OR], 4.41; p<0.01) correlated with increased absenteeism, while a trend toward an association between depression and ED visits (OR, 2.57; p=0.067) was observed. In addition, no association was observed between symptom severity and high absenteeism or ED utilization.

The investigators carried out a cross-sectional cohort study of patients with chronic constipation who presented to a tertiary care centre for anorectal manometry to determine patient characteristics related to increased absenteeism and ED utilization.

Standardized instruments were used to evaluate disease severity, quality of life, somatization and psychiatric comorbidities. Multivariable logistic regression was used to determine the predictors of work and school absenteeism as well as ED visits for constipation.

“Chronic constipation is associated with significant direct and indirect economic costs,” the investigators said. “There has been limited study of the predictors of direct and indirect costs in a population with refractory constipation.”

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Most Read Articles
3 days ago
The consumption of red and processed meats does not seem to affect the likelihood of symptom relapse among Crohn’s disease (CD) patients in relapse, reports a recent study.
Roshini Claire Anthony, 6 days ago

Women who receive a single dose of amoxicillin and clavulanic acid within 6 hours of operative vaginal delivery could significantly reduce their postpartum infection risk, according to the UK-based ANODE* trial.

Pearl Toh, Yesterday
In addition to the known evils of maternal smoking during pregnancy on the son’s semen quality, prenatal exposure to paternal smoking can also be harmful, according to data from a large Danish National Birth Cohort (DNBC) presented at the ESHRE 2019 Meeting.
3 days ago
Treatment with metformin may improve whole-body and peripheral insulin resistance (IR) in youth who are overweight/obese with type 1 diabetes (T1D), according to a study.