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Depression tied to work, school absenteeism in patients with chronic constipation

20 Apr 2018
Men suffering from poor mental health may engage in self-harm or display suicidal thoughts or actions.

Depression appears to be a stronger predictor of absenteeism than symptom severity in patients with chronic constipation, suggests a study, adding that depression may partly contribute to the indirect costs of chronic constipation.

Of the 148 consecutive patients (mean age 43 years; 87 percent female) enrolled in the study, 32 (21.6 percent) had high absenteeism and 36 (24.3 percent) visited the emergency department (ED) for constipation in the past year. Depression was likely in patients with high absenteeism (56.3 percent vs 18.5 percent; p<0.0001) and ED visits (47.2 percent vs 19.6 percent; p<0.01).

Multivariable adjustment and sensitivity analyses revealed that only depression (odds ratio [OR], 4.41; p<0.01) correlated with increased absenteeism, while a trend toward an association between depression and ED visits (OR, 2.57; p=0.067) was observed. In addition, no association was observed between symptom severity and high absenteeism or ED utilization.

The investigators carried out a cross-sectional cohort study of patients with chronic constipation who presented to a tertiary care centre for anorectal manometry to determine patient characteristics related to increased absenteeism and ED utilization.

Standardized instruments were used to evaluate disease severity, quality of life, somatization and psychiatric comorbidities. Multivariable logistic regression was used to determine the predictors of work and school absenteeism as well as ED visits for constipation.

“Chronic constipation is associated with significant direct and indirect economic costs,” the investigators said. “There has been limited study of the predictors of direct and indirect costs in a population with refractory constipation.”

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Most Read Articles
Roshini Claire Anthony, 4 days ago

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Stephen Padilla, 5 days ago
Implementation of the collaborative care in a rheumatoid arthritis (RA) clinic has led to improvements in nonbiologic disease-modifying antirheumatic drugs (nb-DMARDs) optimization, adherence to safety recommendations on nb-DMARD monitoring and detection of adverse drug events in RA patients, according to a Singapore study.
Pearl Toh, 6 days ago
Use of menopausal hormone therapy (MHT) was associated with a significantly increased risk of invasive breast cancer, which became progressively greater with longer duration of use, a meta-analysis of worldwide prospective epidemiological studies has shown.
4 days ago
Blood pressure (BP) in children is influenced by early-life exposure to several chemicals, built environment and meteorological factors, suggests a study.