Most Read Articles
Yesterday
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Pearl Toh, 29 Jun 2020
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
30 Jun 2020
Patients with psoriatic arthritis (PsA) often suffer from liver abnormalities, which are associated with higher body mass index (BMI), daily consumption of alcohol, more severe disease, and some therapies, according to a recent study.
Christina Lau, 5 days ago

Pembrolizumab in combination with chemotherapy significantly improves progression-free survival (PFS) vs chemotherapy alone in patients with previously untreated, locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC), results of the KEYNOTE-355 study have shown.

Depression risk high among spouses of cancer patients

30 May 2020

Spouses of cancer patients are at an elevated risk of major depressive disorder (MDD), a new study has found.

The study included 16,936 married couples with one spouse having cancer, and a comparator group of 168,831 couples where both spouses were cancer-free. Majority of the participants were between 40 and 64 years of age.

Spouses of patients with cancer but without MDD were at a slightly but significantly greater risk of developing MDD themselves as compared to spouses of cancer-free participants (hazard ratio [HR], 1.18, 95 percent confidence interval [CI], 1.03–1.34).

Notably, the effect was stronger in spouses of patients with MDD but without cancer (HR, 2.10, 95 percent CI, 1.50–3.61). Moreover, spouses of patients with both MDD and cancer suffered the greatest risk estimate as compared to spouses of people with neither condition (HR, 2.32, 95 percent CI, 1.50–3.61).

However, compared to cancer patients themselves, spouses were less than half as likely to develop MDD (HR, 0.42, 95 percent CI, 0.36–0.48).

Stratified analyses showed that male spouses aged 65 years were more resilient to MDD than their middle-aged counterparts of the same sex (HR, 0.69, 95 percent CI, 0.55–0.88). On the other hand, spouses of patients younger than 40 years of age suffered from excess MDD risk, with an estimate of borderline significance (HR, 1.23, 95 percent CI, 1.00–1.49). Female spouses also tended to be at greater MDD risk, though statistical significance was not investigated.

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Most Read Articles
Yesterday
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Pearl Toh, 29 Jun 2020
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
30 Jun 2020
Patients with psoriatic arthritis (PsA) often suffer from liver abnormalities, which are associated with higher body mass index (BMI), daily consumption of alcohol, more severe disease, and some therapies, according to a recent study.
Christina Lau, 5 days ago

Pembrolizumab in combination with chemotherapy significantly improves progression-free survival (PFS) vs chemotherapy alone in patients with previously untreated, locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC), results of the KEYNOTE-355 study have shown.