Most Read Articles
Tristan Manalac, 20 Dec 2018
Motor activity appears to play a central role in mood regulation, according to a recent study, which also reports that subjective energy is important in motor activity.
Dr. Joseph Delano Fule Robles, 30 Jan 2019

Five subtypes of insomnia disorder were identified by investigators from The Netherlands, addressing an unmet need to reduce the heterogeneity of insomnia disorder.

12 May 2019
A consistent association exists between perinatal maternal depressive symptoms and child brain development assessed 10 years later, suggests a recent study.
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Depression, sex alter advanced heart failure symptom burden

03 May 2019

Depression appears to increase symptom burden in patients with advanced heart failure (HF), a recent study has found. Burden also seems to be differentiated according to sex.

Researchers enrolled 347 patients with advanced HF (mean age, 66 years; 65 percent male), comparing symptom burden between males and females and between participants with and without depression. The Memorial Symptom Assessment Scale-HF (MSAS-HF) was used to measure symptom burden, while depression was assessed using the Patient Health Questionnaire.

The number of symptoms reported in the overall sample ranged from 0–32, yielding a mean of 13.6±6.8. The most common symptom was pain other than chest pain, which was experienced by 77 percent of the participants. This was followed by shortness of breath (76 percent), lack of energy (76 percent), drowsiness (52 percent), numbness/tingling (60 percent), dry mouth (60 percent) and sleep difficulties (59 percent).

The mean MSAS-HF burden score was 96±58. This was significantly higher in patients with greater depression scores (median, 137 vs 70; p=0.001).

Symptom burden also appeared to be differentially distributed according to sex. Relative to males, females had significantly greater burden of pain other than chest pain (p=0.005), dry mouth (p=0.022), feeling nervous (p=0.041), sweats (p=0.043), vomiting (p=0.015), swelling of the arms and legs (p=0.015), and nausea (p=0.0021).

On the other hand, men reported experiencing significantly greater sexual problems (p≤0.001). No significant differential sex effect was observed for the total symptom burden score (p=0.141).

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Most Read Articles
Tristan Manalac, 20 Dec 2018
Motor activity appears to play a central role in mood regulation, according to a recent study, which also reports that subjective energy is important in motor activity.
Dr. Joseph Delano Fule Robles, 30 Jan 2019

Five subtypes of insomnia disorder were identified by investigators from The Netherlands, addressing an unmet need to reduce the heterogeneity of insomnia disorder.

12 May 2019
A consistent association exists between perinatal maternal depressive symptoms and child brain development assessed 10 years later, suggests a recent study.
07 Sep 2018
Individuals with attention deficiency hyperactivity disorder (ADHD) or anxiety are at greater risk of developing bipolar disorder, according to a study. Moreover, the risk further increases in those who have received diagnoses of both ADHD and anxiety.