Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
Natalia Reoutova, 07 Jan 2020

A prospective cohort study of mothers taking antiepileptic drugs (AEDs) and their breastfed infants has found substantially lower AED concentrations in infant vs maternal blood, with nearly half of all obtained AED concentrations in nursing infants being less than the lower limit of quantification (LLoQ).

5 days ago
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.

Dental care may protect against pneumonia recurrence in kids with neurologic impairment

13 Oct 2019

Dental care has the potential to reduce the recurrence of severe pneumonia in children with neurologic impairment (NI), whereas gastrostomy tube placement is associated with an increased risk of recurrence, possibly due to unresolved confounding by indication, according to a study.

The study included 3,632 children with NI who had been hospitalized for pneumonia. Of these, 1,362 children (37.5 percent) had subsequent pneumonia hospitalization.

Researchers explored potential associations between pneumonia hospitalization recurrence and expert-recommended prevention strategies: dental care, oral secretion management, gastric acid suppression, gastrostomy tube placement, chest physiotherapy, outpatient antibiotics before index hospitalization and clinic visit before or after index hospitalization.

Out of the several pneumonia prevention strategies recommended by expert guidelines, only dental care was associated with reduced risk of subsequent pneumonia hospitalization (adjusted odds ratio [aOR], 0.64, 95 percent CI, 0.49–0.85).

Exposures associated with increased risk, on the other hand, included gastrostomy tube placement (aOR, 2.15, 1.63–2.85), chest physiotherapy (aOR, 2.03, 1.29–3.20), outpatient antibiotics before hospitalization (aOR, 1.42, 1.06–1.92), and clinic visit prior to (aOR, 1.30, 1.11–1.52) and after index hospitalization (aOR, 1.72, 1.35–2.20).

Despite the possible residual confounding by indication, the findings support a clinical trial of dental care for prevention of severe pneumonia in children with NI and discourage the widespread use of gastrostomy tubes for that purpose, according to the researchers.

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Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
Natalia Reoutova, 07 Jan 2020

A prospective cohort study of mothers taking antiepileptic drugs (AEDs) and their breastfed infants has found substantially lower AED concentrations in infant vs maternal blood, with nearly half of all obtained AED concentrations in nursing infants being less than the lower limit of quantification (LLoQ).

5 days ago
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.