Most Read Articles
Stephen Padilla, 06 Aug 2020
The novel coronavirus disease (COVID-19) pandemic appears to have a significant impact on oncological care, according to a study, which stresses the need for psycho-oncological support for cancer patients.
01 Aug 2020
Supplementation with probiotics may have positive effects in patients with type 2 diabetes mellitus (T2DM), reports a recent meta-analysis.
06 Aug 2020
Sodium–glucose cotransporter-2 (SGLT-2) inhibitors increase the risk for diabetic ketoacidosis (DKA) by almost threefold, with molecule-specific analyses suggesting a class effect, according to a study.
Stephen Padilla, 3 days ago
Pre-exposure prophylaxis (PrEP) containing either long-acting injectable cabotegravir (CAB) or tenofovir/emtricitabine (TDF/FTC) is safe and effective for transgender women (TGW) and cisgender men who have sex with men (MSM), but CAB results in a much lower HIV incidence compared to TDF/FTC, results of the HIV Prevention Trials Network (HPTN) 083 have shown.

Dental care may protect against pneumonia recurrence in kids with neurologic impairment

13 Oct 2019

Dental care has the potential to reduce the recurrence of severe pneumonia in children with neurologic impairment (NI), whereas gastrostomy tube placement is associated with an increased risk of recurrence, possibly due to unresolved confounding by indication, according to a study.

The study included 3,632 children with NI who had been hospitalized for pneumonia. Of these, 1,362 children (37.5 percent) had subsequent pneumonia hospitalization.

Researchers explored potential associations between pneumonia hospitalization recurrence and expert-recommended prevention strategies: dental care, oral secretion management, gastric acid suppression, gastrostomy tube placement, chest physiotherapy, outpatient antibiotics before index hospitalization and clinic visit before or after index hospitalization.

Out of the several pneumonia prevention strategies recommended by expert guidelines, only dental care was associated with reduced risk of subsequent pneumonia hospitalization (adjusted odds ratio [aOR], 0.64, 95 percent CI, 0.49–0.85).

Exposures associated with increased risk, on the other hand, included gastrostomy tube placement (aOR, 2.15, 1.63–2.85), chest physiotherapy (aOR, 2.03, 1.29–3.20), outpatient antibiotics before hospitalization (aOR, 1.42, 1.06–1.92), and clinic visit prior to (aOR, 1.30, 1.11–1.52) and after index hospitalization (aOR, 1.72, 1.35–2.20).

Despite the possible residual confounding by indication, the findings support a clinical trial of dental care for prevention of severe pneumonia in children with NI and discourage the widespread use of gastrostomy tubes for that purpose, according to the researchers.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS JPOG - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Stephen Padilla, 06 Aug 2020
The novel coronavirus disease (COVID-19) pandemic appears to have a significant impact on oncological care, according to a study, which stresses the need for psycho-oncological support for cancer patients.
01 Aug 2020
Supplementation with probiotics may have positive effects in patients with type 2 diabetes mellitus (T2DM), reports a recent meta-analysis.
06 Aug 2020
Sodium–glucose cotransporter-2 (SGLT-2) inhibitors increase the risk for diabetic ketoacidosis (DKA) by almost threefold, with molecule-specific analyses suggesting a class effect, according to a study.
Stephen Padilla, 3 days ago
Pre-exposure prophylaxis (PrEP) containing either long-acting injectable cabotegravir (CAB) or tenofovir/emtricitabine (TDF/FTC) is safe and effective for transgender women (TGW) and cisgender men who have sex with men (MSM), but CAB results in a much lower HIV incidence compared to TDF/FTC, results of the HIV Prevention Trials Network (HPTN) 083 have shown.