Most Read Articles
01 Jul 2013

Acne is particularly prevalent during adolescence, and some teenagers will face an on-going battle with this common skin condition.

27 Apr 2017
Lifestyle and physiological factors determine the wrinkling patterns between men and women, a recent study suggests. Less wrinkling is associated with sunburn tendency in men and with female pattern hair loss in women, whereas increased wrinkling is linked to age and current smoking in both genders.
01 Jul 2014

New drug applications approved by US FDA as of 1-15 July which includes New Molecular Entities (NMEs) and new biologics. It includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

01 Mar 2017
The use of multiple dissection planes in endoscope-assisted facelifts of the frontal and temporal areas may be helpful for selected patients, a Singapore study reveals.

Demodex mite infestation high in patients with rosacea

14 Sep 2017

The prevalence and degrees of Demodex mite infestation are higher in patients with rosacea than in control patients, a recent study has found.

Systematic literature review and meta-analysis were conducted to determine the prevalence and degrees of Demodex mite infestation in patients with rosacea. A total of 23 case-control studies were included, which involved 1,513 patients with rosacea.

Researchers pooled odds ratios (ORs) for prevalence of infestation and standardized mean difference (SMD) for Demodex density in patients. They also performed subgroup analysis for type of rosacea, control group, and sampling and examination methods.

Patients with rosacea had significantly higher prevalence of Demodex mite infestation (OR, 9.039; 95 percent CI, 4.827 to 16.925) and significantly greater Demodex density (SMD, 1.617; 1.090 to 2.145) compared with the control patients. Furthermore, both erythematotelangiectatic rosacea (SMD, 2.686; 1.256 to 4.116) and papulopustular rosacea (SMD, 2.804; 1.464 to 4.145) had significantly higher Demodex density than did healthy control patients.

These findings suggest that “Demodex mites may play a role in both erythematotelangiectatic rosacea and papulopustular rosacea,” according to researchers, adding that their systematic review and meta-analysis were limited by a high interstudy variability and the failure to establish causal relationship due to the design of the included studies.

In an earlier study, the investigators concluded that although Demodex mites did not appear to cause rosacea, they might represent an important cofactor, especially in papulopustular rosacea. Immunohistochemical findings suggested that a delayed hypersensitivity reaction, possibly related to D. folliculorum, might occur, stimulating progression of the affection to the papulopustular stage. [J Eur Acad Dermatol Venereol 2001 Sep;15(5):441-4]

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Most Read Articles
01 Jul 2013

Acne is particularly prevalent during adolescence, and some teenagers will face an on-going battle with this common skin condition.

27 Apr 2017
Lifestyle and physiological factors determine the wrinkling patterns between men and women, a recent study suggests. Less wrinkling is associated with sunburn tendency in men and with female pattern hair loss in women, whereas increased wrinkling is linked to age and current smoking in both genders.
01 Jul 2014

New drug applications approved by US FDA as of 1-15 July which includes New Molecular Entities (NMEs) and new biologics. It includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

01 Mar 2017
The use of multiple dissection planes in endoscope-assisted facelifts of the frontal and temporal areas may be helpful for selected patients, a Singapore study reveals.