Most Read Articles
Elaine Soliven, 5 days ago

Switching from efavirenz/emtricitabine/tenofovir disoproxil fumarate (EFV/FTC/TDF) to the new bictegravir/ emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) regimen maintained high rates of virological suppression in adults who are living with HIV*, according to a study presented at AIDS 2020.

3 days ago
Among individuals with abdominal obesity, drinking beverages with artificial sweeteners (ASBs) or no sugar (USBs) instead of sugar-sweetened beverages (SSBs) helps lose body weight, a study has found. However, USBs have a more favourable effect on sweet taste preference compared with ASBs.
Stephen Padilla, 5 days ago
Pre-exposure prophylaxis (PrEP) containing either long-acting injectable cabotegravir (CAB) or tenofovir/emtricitabine (TDF/FTC) is safe and effective for transgender women (TGW) and cisgender men who have sex with men (MSM), but CAB results in a much lower HIV incidence compared to TDF/FTC, results of the HIV Prevention Trials Network (HPTN) 083 have shown.
Jairia Dela Cruz, 4 days ago
Monthly prophylaxis with the fixed-dose combination of naphthoquine-azithromycin (NQAZ) is well tolerated and confers significant protection against infection with Plasmodium parasites among individuals residing in malaria-endemic areas in Southeast Asia, as shown in the results of a phase III trial.

CVD risk lower in prostate cancer survivors

11 Jul 2020
Prostate cancer is a silent killer. Many may not be aware of the illness until it is too late.

The risk of cardiovascular diseases (CVDs) appear to be lower among survivors of prostate cancer (PC), a recent study has found.

The study included 48,298 PC patients, who were age-matched 1:3 with a general-population control. The study endpoints were newly diagnosed stroke or ishaemic heart disease (IHD), as well as death. Participants who were below 19 years of age, had other cancers, or had a previous history of IHD were deemed ineligible.  

The final screening cohort included 29,365 PC survivors who had been matched to 105,347 noncancer comparators. Over a mean follow-up of 3.65 and 3.85 years, respectively, PC survivors carried a slightly but significantly lower risk of IHD than controls (adjusted hazard ratio [HR], 0.89, 95 percent confidence interval [CI], 0.83–0.96).

This protective effect was also found for stroke (adjusted HR, 0.90, 95 percent CI, 0.86–0.95). On the other hand, the risk of death was higher in PC survivors (adjusted HR, 1.61, 95 percent CI, 1.57–1.64).

Treatment approach appeared to affect this interaction, the researchers reported. Patients who underwent curative surgery had better IHD outlook than controls (adjusted HR, 0.69, 95 percent CI, 0.56–0.85). The same was true for stroke (adjusted HR, 0.75, 95 percent CI, 0.65–0.87).

Patients who received androgen deprivation therapy on top of surgery also saw a marginally lower risk of stroke than controls (adjusted HR, 0.78, 95 percent CI, 0.67–0.91). On the other hand, those who were under active surveillance/watchful waiting had a similar CVD risk as noncancer controls.

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Most Read Articles
Elaine Soliven, 5 days ago

Switching from efavirenz/emtricitabine/tenofovir disoproxil fumarate (EFV/FTC/TDF) to the new bictegravir/ emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) regimen maintained high rates of virological suppression in adults who are living with HIV*, according to a study presented at AIDS 2020.

3 days ago
Among individuals with abdominal obesity, drinking beverages with artificial sweeteners (ASBs) or no sugar (USBs) instead of sugar-sweetened beverages (SSBs) helps lose body weight, a study has found. However, USBs have a more favourable effect on sweet taste preference compared with ASBs.
Stephen Padilla, 5 days ago
Pre-exposure prophylaxis (PrEP) containing either long-acting injectable cabotegravir (CAB) or tenofovir/emtricitabine (TDF/FTC) is safe and effective for transgender women (TGW) and cisgender men who have sex with men (MSM), but CAB results in a much lower HIV incidence compared to TDF/FTC, results of the HIV Prevention Trials Network (HPTN) 083 have shown.
Jairia Dela Cruz, 4 days ago
Monthly prophylaxis with the fixed-dose combination of naphthoquine-azithromycin (NQAZ) is well tolerated and confers significant protection against infection with Plasmodium parasites among individuals residing in malaria-endemic areas in Southeast Asia, as shown in the results of a phase III trial.