Most Read Articles
Pearl Toh, 19 Jun 2016
Infants with persistent rhinitis have a higher abundance of Actinobacteria, especially Corynebacterium spp., in their nasal microbiome compared with healthy controls, according to a Singapore-based study presented at the European Academy of Allergy and Clinical Immunology (EAACI) Annual Congress 2016 held in Vienna, Austria.
29 Nov 2017
Lansoprazole, a widely available and commonly prescribed proton pump inhibitor (PPI), appears to reduce the incidence of tuberculosis disease, a recent study has found.
Gabriel Angelo Sembrano, 16 Sep 2014

“At present, there is a limited development of new antibiotics. There is also a fast development of resistance to antibiotics. There are pathogens no longer susceptible to all antibiotics, and many pathogens are no longer susceptible to most antibiotics,” said Dr. Andre Villanueva, chief of party of the USAID’s Innovations and Multisectoral Partnerships to Achieve Control of TB (IMPACT) Project at the recent Annual Convention of the Philippine Pharmacists’ Association in Davao City.

Pearl Toh, 31 May 2016
Synbiotic mixture of oligosaccharides and Bifidobacterium breve (B. breve) M-16V probiotic strain in infant formula restores gut colonisation by B. breve and supports healthy gut development in infants delivered by Caesarean-section (C-section), according to a study presented at the recent European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) annual meeting held in Athens, Greece.

Cross-linked N-telopeptide of type I collagen predicts bone metastasis in lung cancer

06 Dec 2017

Elevated levels of cross-linked N-telopeptide of type I collagen (NTx) appear to raise the risk of development and progression of bone metastasis (BM) in lung cancer patients, a recent study reveals.

The research team performed a meta-analysis of 11 studies (n=1,108) that compared the expression levels of NTx between lung cancer patients with and without BM. Aside from a review of study references, the databases of Web of Science, CNKI, Wangfang, PubMed and Embase were accessed for the present study.

Pooled findings from eight studies showed that patients positive for BM had significantly higher serum NTx concentrations than their BM-negative counterparts (weighted mean difference [WMD], -11.57 percent; 95 percent CI, -15.14 to -8.00).

Similarly, urinary levels of NTx, investigated in three studies, were also found to be significantly higher in patients with BM than those without (WMD, -65.15 percent; -88.33 to -41.97).

The pooled sensitivity and specificity of serum NTx in discerning BM from non-BM lung cancer patients were 0.74 (0.67 to 0.79) and 0.85 (0.80 to 0.89), respectively. In comparison, the corresponding values for urinary NTx were 0.77 (0.67 to 0.86) and 0.81 (0.76 to 0.86).

Both serum and urinary NTx had similar and good diagnostic accuracy, with respective diagnostic odds ratios of 15.07 (9.6 to 23.65) and 15.25 (8.38 to 27.73). The respective areas under the receiver operating curve for both were 0.8889 and 0.8655, which suggests that both samples could accurately distinguish between patients with and without BM.

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Most Read Articles
Pearl Toh, 19 Jun 2016
Infants with persistent rhinitis have a higher abundance of Actinobacteria, especially Corynebacterium spp., in their nasal microbiome compared with healthy controls, according to a Singapore-based study presented at the European Academy of Allergy and Clinical Immunology (EAACI) Annual Congress 2016 held in Vienna, Austria.
29 Nov 2017
Lansoprazole, a widely available and commonly prescribed proton pump inhibitor (PPI), appears to reduce the incidence of tuberculosis disease, a recent study has found.
Gabriel Angelo Sembrano, 16 Sep 2014

“At present, there is a limited development of new antibiotics. There is also a fast development of resistance to antibiotics. There are pathogens no longer susceptible to all antibiotics, and many pathogens are no longer susceptible to most antibiotics,” said Dr. Andre Villanueva, chief of party of the USAID’s Innovations and Multisectoral Partnerships to Achieve Control of TB (IMPACT) Project at the recent Annual Convention of the Philippine Pharmacists’ Association in Davao City.

Pearl Toh, 31 May 2016
Synbiotic mixture of oligosaccharides and Bifidobacterium breve (B. breve) M-16V probiotic strain in infant formula restores gut colonisation by B. breve and supports healthy gut development in infants delivered by Caesarean-section (C-section), according to a study presented at the recent European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) annual meeting held in Athens, Greece.