Most Read Articles
Naomi Rodrig, 09 Oct 2017

New endoscopic technologies have improved outcomes for patients with upper gastrointestinal bleeding (UGIB), according to Professor James Lau from the Chinese University of Hong Kong, who reviewed current treatment practices and latest advances at the Asian Pacific Digestive Week (APDW) 2017 held recently in Hong Kong.

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The efficacy of endoscopic ultrasound-guided gastrojejunostomy (EUS-GJ) is comparable with that of laparoscopic gastrojejunostomy (Lap-GJ), but the former has more complex patients with gastric outlet obstruction (GOO), reports a recent study. Furthermore, the EUS-GJ group has significantly lower adverse events.
30 Oct 2017
Children with autism spectrum disorders (ASD) appear to have significantly altered gut mucosal mitochondrial function compared with controls and other children with nonspecific gastrointestinal symptoms, a recent study shows.
Jairia Dela Cruz, 07 Oct 2017
Serum albumin appears to be useful in predicting early mortality in Asian patients with severe hypoxic hepatitis, with low baseline levels entailing a fivefold increase in risk of death, as shown in a Singapore study.

Crohn’s disease poses increased risk of ectopic pregnancy

14 Sep 2017

Women with Crohn’s disease are at greater risk of ectopic pregnancies compared with those who do not have inflammatory bowel disease (IBD), a recent study suggests. Moreover, undergoing a surgery for IBD prior to pregnancy appears to contribute to a nonsignificant increase in risk of the pregnancy complication.

Using a large national patient registry in Denmark, researchers evaluated the risk of an ectopic pregnancy over a 22-year period in 7,548 pregnancies in women with ulcerative colitis, 6,731 pregnancies in women with CD and 1,832,732 pregnancies in those without IBD. Disease-specific risks of ectopic pregnancies were also evaluated in pregnancies of women with UC or CD who underwent IBD-related surgical procedures.

Logistic regression analysis found that the risk of ectopic pregnancy, per pregnancy, was higher in women with CD (odds ratio [OR], 1.23; 95 percent CI, 1.01 to 1.49) and did not increase in women with UC (OR, 0.98; 0.80 to 1.20) compared with women who did not have IBD.

Furthermore, a nonsignificant increase in risk of ectopic pregnancy was observed in pregnancies of women with CD or UC who underwent IBD-related surgery before pregnancy vs pregnancies in women with IBD who did not have surgery (CD: OR, 1.49; 0.91 to 2.44; UC: OR, 1.17; 0.54 to 2.52).

While the overall absolute risk of ectopic pregnancy remains low, the reported increase in relative risk of the said pregnancy complication in women with CD provides useful information for clinicians managing female IBD patients of reproductive age and heightens awareness of the possibility of ectopic complications in this patient group, researchers pointed out.

“In general, women with IBD should be educated about risk factors for EP such as pelvic infections and assisted reproductive technology,” researchers said, adding that the present data should be confirmed in other settings.

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Most Read Articles
Naomi Rodrig, 09 Oct 2017

New endoscopic technologies have improved outcomes for patients with upper gastrointestinal bleeding (UGIB), according to Professor James Lau from the Chinese University of Hong Kong, who reviewed current treatment practices and latest advances at the Asian Pacific Digestive Week (APDW) 2017 held recently in Hong Kong.

27 Oct 2017
The efficacy of endoscopic ultrasound-guided gastrojejunostomy (EUS-GJ) is comparable with that of laparoscopic gastrojejunostomy (Lap-GJ), but the former has more complex patients with gastric outlet obstruction (GOO), reports a recent study. Furthermore, the EUS-GJ group has significantly lower adverse events.
30 Oct 2017
Children with autism spectrum disorders (ASD) appear to have significantly altered gut mucosal mitochondrial function compared with controls and other children with nonspecific gastrointestinal symptoms, a recent study shows.
Jairia Dela Cruz, 07 Oct 2017
Serum albumin appears to be useful in predicting early mortality in Asian patients with severe hypoxic hepatitis, with low baseline levels entailing a fivefold increase in risk of death, as shown in a Singapore study.