Most Read Articles
12 May 2016

A study published in Science shows new strains of microbes from the donor were more likely to colonize the patient’s intestines if that particular species exists in the patient’s gut.

Rachel Soon, 18 Jan 2017

Patients infected with Helicobacter pylori strains derived from different geographical human ancestries than their own are likely to develop more severe symptoms which include gastric cancers, says an expert.

Jairia Dela Cruz, 19 Oct 2017
Having both type 1 diabetes and coeliac disease (CD) autoimmunity in early childhood appears to be more common than expected, with the development of islet autoantibodies (IAs) conferring a significant risk of subsequent tissue transglutaminase autoantibodies (tTGAs), according to data from the TEDDY* study.
Pank Jit Sin, 27 Dec 2017
The addition of synbiotics to the diet of adults suffering from functional constipation may lead to significant improvement in constipation syndroms. 

Crohn’s disease poses increased risk of ectopic pregnancy

14 Sep 2017

Women with Crohn’s disease are at greater risk of ectopic pregnancies compared with those who do not have inflammatory bowel disease (IBD), a recent study suggests. Moreover, undergoing a surgery for IBD prior to pregnancy appears to contribute to a nonsignificant increase in risk of the pregnancy complication.

Using a large national patient registry in Denmark, researchers evaluated the risk of an ectopic pregnancy over a 22-year period in 7,548 pregnancies in women with ulcerative colitis, 6,731 pregnancies in women with CD and 1,832,732 pregnancies in those without IBD. Disease-specific risks of ectopic pregnancies were also evaluated in pregnancies of women with UC or CD who underwent IBD-related surgical procedures.

Logistic regression analysis found that the risk of ectopic pregnancy, per pregnancy, was higher in women with CD (odds ratio [OR], 1.23; 95 percent CI, 1.01 to 1.49) and did not increase in women with UC (OR, 0.98; 0.80 to 1.20) compared with women who did not have IBD.

Furthermore, a nonsignificant increase in risk of ectopic pregnancy was observed in pregnancies of women with CD or UC who underwent IBD-related surgery before pregnancy vs pregnancies in women with IBD who did not have surgery (CD: OR, 1.49; 0.91 to 2.44; UC: OR, 1.17; 0.54 to 2.52).

While the overall absolute risk of ectopic pregnancy remains low, the reported increase in relative risk of the said pregnancy complication in women with CD provides useful information for clinicians managing female IBD patients of reproductive age and heightens awareness of the possibility of ectopic complications in this patient group, researchers pointed out.

“In general, women with IBD should be educated about risk factors for EP such as pelvic infections and assisted reproductive technology,” researchers said, adding that the present data should be confirmed in other settings.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Gastroenterology - Malaysia digital copy today!
DOWNLOAD
Editor's Recommendations
Most Read Articles
12 May 2016

A study published in Science shows new strains of microbes from the donor were more likely to colonize the patient’s intestines if that particular species exists in the patient’s gut.

Rachel Soon, 18 Jan 2017

Patients infected with Helicobacter pylori strains derived from different geographical human ancestries than their own are likely to develop more severe symptoms which include gastric cancers, says an expert.

Jairia Dela Cruz, 19 Oct 2017
Having both type 1 diabetes and coeliac disease (CD) autoimmunity in early childhood appears to be more common than expected, with the development of islet autoantibodies (IAs) conferring a significant risk of subsequent tissue transglutaminase autoantibodies (tTGAs), according to data from the TEDDY* study.
Pank Jit Sin, 27 Dec 2017
The addition of synbiotics to the diet of adults suffering from functional constipation may lead to significant improvement in constipation syndroms.