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01 Apr 2016
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CPAP for sleep apnoea does not enhance asthma control, but improves daytime sleepiness, QoL

05 Nov 2018

There appears to be a high prevalence of obstructive sleep apnoea syndrome (OSAS) among patients with asthma and snoring, reports a study. Continuous positive airway pressure (CPAP) treatment for 3 months does not improve asthma control but enhances daytime sleepiness, quality of life and vitality.

A total of 145 patients were recruited, of which 122 underwent sleep study with 41 (33.6 percent) having apnoea–hypopnoea index (AHI) ≥10/h. The following characteristics were observed in patients with significant OSAS: higher body mass index (27.4 vs 25.1 kg/m2; p=0.016), bigger neck circumference (36.6 vs 34.8 cm; p=0.006) and lower minimum SaO2 (80.7 vs 87.2 percent; p<0.001).

Intention-to-treat analysis among 37 patients with AHI ≥10/h (CPAP group [n=17] vs control group [n=20]) showed no significant between-group difference in Asthma Control Test score (3.2 vs 2.4; p=0.568), but the CPAP group had a greater improvement in Epworth Sleepiness Scale (–3.0 vs 0.5; p=0.014), Asthma Quality of Life Questionnaire (0.6 vs 0.02; p=0.022) and vitality domain in the SF-36 questionnaire (14.7 vs 0.3; p=0.012) after 3 months.

This study examined asthma control, airway responsiveness, daytime sleepiness and health status at baseline and 3 months after CPAP therapy among asthma patients with nocturnal symptoms and OSAS.

Using Embletta portable diagnostic system, patients with nocturnal asthma symptoms despite receiving at lease moderate-dose inhaled corticosteroid and long-acting bronchodilators underwent a home sleep study. Those with significant OSAS were randomly assigned to receive either CPAP or conservative treatment for 3 months.

“Unrecognized OSAS may lead to poor asthma control despite optimal therapy,” the authors said.

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Most Read Articles
01 Apr 2016
Posaconazole oral suspension may be effective in managing fungal infections among lung transplant recipients, as presented in a single-centre, retrospective study.
Saras Ramiya, 19 Nov 2018
Sunway Medical Centre is collaborating with Royal Papworth Hospital to facilitate knowledge exchange among cardiology and respiratory experts.
Tristan Manalac, 11 Sep 2018
The immediate reduction of cigarette nicotine content results in greater improvements in levels of smoke exposure biomarkers than gradual reduction, though withdrawal symptoms are stronger, according to a recent study.
Stephen Padilla, 10 Jan 2019
Happy Quit, a mobile-phone-based text messaging intervention, has led smokers in a China study to stop smoking with either high- (HFM) or low-frequency messaging (LFM). This intervention may be paired with other smoking cessation services for treatment-seeking smokers.