Most Read Articles
Jairia Dela Cruz, 22 Apr 2020
A wristwatch-like device that monitors pulse, breathing and blood oxygen levels of the user allows physicians to provide care remotely both in hospital and nontraditional settings, and may help in the fight against the coronavirus disease 2019 (COVID-19) pandemic.
Roshini Claire Anthony, 6 days ago

The use of a vaginal cleansing intervention prior to Caesarean delivery reduced the incidence of surgical site infections (SSIs), according to a study presented at ACOG 2020. However, the addition of intravenous (IV) azithromycin prophylaxis had no added impact on SSI rates. 

Pank Jit Sin, 21 May 2020

Persons suffering from asthma should pay particular attention to SARS-CoV-2 precautionary measures such as social distancing, regular handwashing, and wearing of masks on top of keeping their asthma in control. This is because data collected so far paints a bleaker picture for asthmatics than the normal population should they catch COVID-19.

Stephen Padilla, 5 days ago
Herd immunity will not work in the novel coronavirus disease (COVID-19), according to an infectious disease expert who addressed over 3,600 primary care physicians (PCP) from Asia Pacific at the inaugural webcast of the MIMS COVID Conversations Series.

COVID-19 viral shedding can last for up to 50 days

02 Apr 2020
The many virus pandemics in the past millennium may provide clues for the current battle against HIV/AIDS.

A new study reports a case of mild coronavirus disease 2019 (COVID-19) but with an unusually long period of viral shedding, reaching nearly 50 days.

The patient, a middle-aged man, presented with intermittent fever lasting for about 1 week. Other symptoms of COVID-19, such as stuffiness, headaches, chest pain, shortness of breath or diarrhoea, were absent. Close relatives tested positive for the infection a day prior to presentation.

Upon clinical examination, the patient had a body temperature of 36.2 oC and laboratory tests found were unremarkable, with normal levels of white blood cells, lymphocytes and neutrophils. Chest computed tomography showed signs of infection, though nasopharyngeal swabs also returned negative for influenza A and B.

The patient eventually tested positive for COVID-19 and, on days 2 to 5 of being hospitalized, developed fevers reaching just under 37.5 oC. This normalized by day 6 and, along with other disease indicators, remained stable for the remainder of hospitalization.

Routine testing on oropharyngeal swabs confirmed that the patient was positive for COVID-19 on days 17, 22, 26 and 30. Notably, the positive result persisted beyond this point, indicating viral shedding at days 34, 39 and 43. The final positive test was obtained on day 49.

Given the prolonged infection, the patient was subjected to plasma infusion, leading to high fever which subsided after a day. Subsequent viral tests returned negative.

Future studies are needed to confirm the beneficial effects of plasma therapy on COVID-19 patients and to determine the role that such prolonged viral shedding can have on the course of the outbreak, the researchers said.

This study is a preprint and is not yet peer reviewed.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Infectious Diseases - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Jairia Dela Cruz, 22 Apr 2020
A wristwatch-like device that monitors pulse, breathing and blood oxygen levels of the user allows physicians to provide care remotely both in hospital and nontraditional settings, and may help in the fight against the coronavirus disease 2019 (COVID-19) pandemic.
Roshini Claire Anthony, 6 days ago

The use of a vaginal cleansing intervention prior to Caesarean delivery reduced the incidence of surgical site infections (SSIs), according to a study presented at ACOG 2020. However, the addition of intravenous (IV) azithromycin prophylaxis had no added impact on SSI rates. 

Pank Jit Sin, 21 May 2020

Persons suffering from asthma should pay particular attention to SARS-CoV-2 precautionary measures such as social distancing, regular handwashing, and wearing of masks on top of keeping their asthma in control. This is because data collected so far paints a bleaker picture for asthmatics than the normal population should they catch COVID-19.

Stephen Padilla, 5 days ago
Herd immunity will not work in the novel coronavirus disease (COVID-19), according to an infectious disease expert who addressed over 3,600 primary care physicians (PCP) from Asia Pacific at the inaugural webcast of the MIMS COVID Conversations Series.