Most Read Articles
5 days ago
In patients with type 2 diabetes, obesity may be protective against vision-threatening diabetic retinopathy, a recent Korea study has shown.
Roshini Claire Anthony, 4 days ago

Men with metastatic hormone-sensitive prostate cancer (mHSPC) who receive testosterone suppression therapy may have a better survival outcome with the addition of enzalutamide over other non-steroidal anti-androgen (NSAA) therapies, according to the phase III ENZAMET* trial.

07 Jun 2019
Low-dose aspirin therapy does not confer significant benefits to elderly patients with hypertension, but treatment appears to increase the risk of haemorrhagic events, suggest a Japan study.
4 days ago
The use of opioids may have limited long-term efficacy in the management of chronic noncancer pain, reports a new study.

Continuation of biologics therapy improves flare during pregnancy

19 Dec 2018
Biosimilar versus Generic: How similar are they?

Continued use of biologics therapy among women with psoriatic arthritis (PsA) appears to reduce the level of disease activity and probability of flare during pregnancy, while stopping treatment prior to conception correlates with flare during pregnancy and the postpartum period, a study has shown.

A total of 25 women with PsA and 35 pregnancies were included. Of the pregnancies, 33 resulted in live healthy babies. No significant change was observed in disease activity throughout pregnancy in the whole group, while patients in 16 pregnancies (48 percent) worsened during the first postpartum year.

Of the 21 pregnancies in which women had been treated with biologics prior to conception, 15 discontinued treatment close to pregnancy or during the first trimester. Five of those 15 patients had been classified as having mild to severe PsA activity before pregnancy. This number rose to eight, nine and 14 during the first and second trimesters and postpartum period, respectively.

The degree of disease activity did not significantly change in six patients who continued using the biologics therapy beyond the first trimester. Nonbiologics-treated patients also showed improvement in disease activity during pregnancy.

Corticosteroids were administered or the dosage was increased during six pregnancies in patients whose biologics were ceased prior to conception.

This retrospective case series sought to assess the effect of pregnancy on disease activity in PsA. The authors reviewed the medical files of all female patients followed at the PsA clinic of two medical centres and identified those with at least one pregnancy during follow-up and one visit during or soon after pregnancy.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
5 days ago
In patients with type 2 diabetes, obesity may be protective against vision-threatening diabetic retinopathy, a recent Korea study has shown.
Roshini Claire Anthony, 4 days ago

Men with metastatic hormone-sensitive prostate cancer (mHSPC) who receive testosterone suppression therapy may have a better survival outcome with the addition of enzalutamide over other non-steroidal anti-androgen (NSAA) therapies, according to the phase III ENZAMET* trial.

07 Jun 2019
Low-dose aspirin therapy does not confer significant benefits to elderly patients with hypertension, but treatment appears to increase the risk of haemorrhagic events, suggest a Japan study.
4 days ago
The use of opioids may have limited long-term efficacy in the management of chronic noncancer pain, reports a new study.