Most Read Articles
Roshini Claire Anthony, 29 May 2020

For coffee drinkers, drinking filtered coffee may be tied to a lower mortality risk, including cardiovascular disease (CVD)-related mortality, a study from Norway suggested.

5 days ago
Use of corticosteroid is not associated with improved outcomes in idiopathic pulmonary fibrosis (IPF) patients admitted to the hospital with acute exacerbation (AE), reveals a recent study. In addition, corticosteroids may even contribute to reduced overall survival following exacerbation.
Dr. Wong Soon Tee, 28 May 2020
Acne is a common skin problem seen in primary care. Dr Wong Soon Tee of Assurance Skin Clinic at Mt Elizabeth Novena Hospital, Singapore shares his insights with Pearl Toh on how to manage acne in the primary care setting.
27 May 2020
The perception that proton pump inhibitors (PPIs) cause multiple serious adverse effects (AEs) is supported by many internists, who then recommend treatment cessation even in patients at high risk for upper gastrointestinal bleeding (UGIB), reveals a study.

Conditions, surgeries tied to decreased gastric acid associated with SIBO diagnosis

23 Jan 2020

Conditions of and surgery causing decreased gastric acid correlate with small intestinal bacterial overgrowth (SIBO) diagnosis by culture, a recent study has shown.

Of the 76 patients included, 37 had SIBO (68 percent coliform; 33 percent upper aerodigestive tract [UAT]) and 39 had none. Conditions (p=0.02) and surgery (p<0.01) related to decreased gastric acid were associated with SIBO.

Multinomial logistic regression revealed an association between conditions of decreased acid and UAT SIBO (odds ratio [OR], 5.8, 95 percent confidence interval [CI], 1.4–33.3). Surgery causing decreased acid correlated with UAT (OR, 9.5, 95 percent CI, 1.4–106) and coliform SIBO (OR, 8.4, 95 percent CI, 1.6–86.4). Coliform SIBO was detected in three patients with discontinuous small bowel (OR, 17.4, 95 percent CI, 1.2–2,515).

No differences were observed in complications, overall symptoms, quality of life or psychological traits.

In this study, small bowel aspirates were cultured in patients with suspected SIBO, defined as ≥104 colony-forming units/mL coliform or ≥105 colony-forming units/mL UAT bacteria. The investigators reviewed patient history for risk factors and potential SIBO complications, and evaluated symptoms, quality of life, psychological traits and laboratory values.

Groups were compared by 2-sample t-test, Wilcoxon rank sum test and the Fisher exact test. Analysis of variance F-test, Kruskal-Wallis test, and the Fisher exact tests was conducted to assess overall associations of primary and secondary endpoints with bacterial overgrowth type. Multinomial logistic regression was performed to examine the associations between risk factors and overgrowth type.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 29 May 2020

For coffee drinkers, drinking filtered coffee may be tied to a lower mortality risk, including cardiovascular disease (CVD)-related mortality, a study from Norway suggested.

5 days ago
Use of corticosteroid is not associated with improved outcomes in idiopathic pulmonary fibrosis (IPF) patients admitted to the hospital with acute exacerbation (AE), reveals a recent study. In addition, corticosteroids may even contribute to reduced overall survival following exacerbation.
Dr. Wong Soon Tee, 28 May 2020
Acne is a common skin problem seen in primary care. Dr Wong Soon Tee of Assurance Skin Clinic at Mt Elizabeth Novena Hospital, Singapore shares his insights with Pearl Toh on how to manage acne in the primary care setting.
27 May 2020
The perception that proton pump inhibitors (PPIs) cause multiple serious adverse effects (AEs) is supported by many internists, who then recommend treatment cessation even in patients at high risk for upper gastrointestinal bleeding (UGIB), reveals a study.