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6 days ago
Regular practice of yoga postures confers benefits for glucose control, oxidative stress, inflammatory response, and sleep quality in patients with type 2 diabetes, a study has found.
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
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Computer-aided colonoscopy minimizes adenoma miss rate

01 Nov 2020
Although the prevalence for perforation during colonoscopy is small, patients should not neglect the underlying medical risks.

Computer-aided detection (CADe) systems help reduce adenoma miss rate during colonoscopy, a new study has found.

Researchers conducted a prospective study of patients referred for diagnostic or surveillance colonoscopies. Participants were randomly assigned to receive routine (n=185; mean age, 47.19±10.38 years) or CADe-assisted (n=184; mean age, 47.72±10.82 years) colonoscopies. All patients also underwent a second-pass colonoscopy using the opposite method.

Adenoma miss rate (AMR), the number of adenomas detected in the second-pass round divided by the total number of adenomas, was the primary outcome.

The AMR was significantly lower in the CADe procedures than in the routine white light colonoscopies (13.89 percent vs 40.00 percent; p<0.0001), as was the polyp miss rate (12.98 percent vs 45.90 percent; p<0.0001).

The overall adenoma (ADR) and polyp (PDR) detection rates, as well as adenoma (APC) and polyp (PPC) per colonoscopy, did not differ between patients who underwent either CADe or routine colonoscopy during the first-pass round. However, the PDR (p=0.001), APC (p<0.001), and PPC (p<0.001) were all significantly better when CADe colonoscopy was performed for the first-pass.

Similarly, CADe colonoscopy for the second pass yielded significantly better PDR (p<0.001), APC (p=0.001), and PPC (p<0.001) values, as well as ADR (p=0.043).

On the other hand, CADe colonoscopy consistently detected false polyps (n=67), which were features continuously traced by the CADe system but ultimately deemed as not polyps by the endoscopists. There were no missed polyps.

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Most Read Articles
6 days ago
Regular practice of yoga postures confers benefits for glucose control, oxidative stress, inflammatory response, and sleep quality in patients with type 2 diabetes, a study has found.
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
6 days ago
Women with central adiposity, regardless of menopausal status, are at risk of developing breast cancer, according to a study.