Most Read Articles
01 Nov 2019
Women with hypertensive disorders of pregnancy, especially pre-eclampsia, are at heightened risk of developing cardiovascular disorder and chronic hypertension, with the risk becoming apparent soon after pregnancy, a study has found.
Roshini Claire Anthony, 29 May 2019

Gestational diabetes and abnormal glucose levels in pregnancy, as determined with an oral glucose challenge test (OGCT) at 24–28 weeks gestation, could signal a future risk of cardiovascular disease (CVD)*, according to a recent study.

07 Jul 2019
Plasma creatinine kinase activity, measure during early pregnancy, influences blood pressure during pregnancy and contributes to severe gestational hypertension diagnosed before 34 weeks of gestation, according to a recent study. There is no association between creatinine kinase and other hypertensive disorders during pregnancy.
Pank Jit Sin, 16 Oct 2019
While a diagnosis of cancer is often met with concern and devastation, the same is barely true for heart failure. However, the mortality rate for those suffering from heart failure is worse than some common cancers, such as prostate and breast cancers. 

Complex congenital heart disease compromises body composition

13 Oct 2019

Adults with complex congenital heart disease (CHD) have lower skeletal muscle mass and are more likely to have sarcopoenia, a recent study has found.

Seventy-three complex CHD patients (mean age, 35.8±14.3 years; 22 females) underwent dual-energy x-ray absorptiometry (DXA) for the measurement of body composition. Those with low skeletal muscle mass in relation to height and weight were identified as sarcopoenic. Seventy-three age- and sex-matched controls were also included.

In the overall sample, complex CHD patients were significantly shorter than their control counterparts (173.2±9.7 vs 176.6±9.2 cm; p=0.029), while also having lower total lean mass (48.3±8.7 vs 53.3±9.6 kg; p=0.001), appendicular lean mass (21.69±4.70 vs 24.95±5.28; p<0.001), and isometric strength of the biceps (p=0.004), quadriceps (p=0.002) and unilateral grip (p=0.002).

Relative tissue fat mass, on the other hand, was significantly elevated in those with complex CHD (31.8±9.3 vs 27.4±8.7 percent; p=0.003).

Analysis according to sex showed that the effect of complex CHD was stronger in females, where almost all anthropometric, DXA and isometric strength domains were significantly worse in patients than in controls. The only exceptions were weight and hip circumference. Male patients were shorter and lighter than controls, and had worse DXA results and isometric strength.

Despite these findings, researchers noted that the both the muscle and fat differences between patients and controls could be made up for by behavioural changes. “Perhaps the next step toward a longer and healthier life for adults with congenital heart disease lies in a more structured follow-up programme promoting individualized training regimen and a healthy diet.”

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Cardiology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
01 Nov 2019
Women with hypertensive disorders of pregnancy, especially pre-eclampsia, are at heightened risk of developing cardiovascular disorder and chronic hypertension, with the risk becoming apparent soon after pregnancy, a study has found.
Roshini Claire Anthony, 29 May 2019

Gestational diabetes and abnormal glucose levels in pregnancy, as determined with an oral glucose challenge test (OGCT) at 24–28 weeks gestation, could signal a future risk of cardiovascular disease (CVD)*, according to a recent study.

07 Jul 2019
Plasma creatinine kinase activity, measure during early pregnancy, influences blood pressure during pregnancy and contributes to severe gestational hypertension diagnosed before 34 weeks of gestation, according to a recent study. There is no association between creatinine kinase and other hypertensive disorders during pregnancy.
Pank Jit Sin, 16 Oct 2019
While a diagnosis of cancer is often met with concern and devastation, the same is barely true for heart failure. However, the mortality rate for those suffering from heart failure is worse than some common cancers, such as prostate and breast cancers.