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Mental health comorbidities are common among patients with type 2 diabetes mellitus and may lead to worse outcomes, a recent study has found.
Roshini Claire Anthony, 13 Nov 2020

Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.

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Comorbidities worsen HRQoL after surgery in patients with differentiated thyroid carcinoma

16 Apr 2020

Patients with differentiated thyroid carcinoma (DTC) who had undergone thyroidectomy suffer from poorer health-related quality of life (HRQoL), which may be exacerbated by comorbidities, a recent study has found.

The study included 174 DTC patients who underwent thyroidectomy and 174 matched controls. The 36-item Short Form (SF-36) survey was used to measure HRQoL, and structured questionnaires were used to collect sociodemographic and comorbidity information.

At the 1-year follow-up, DTC patients scored significantly lower on almost all domains of the SF-36 questionnaire. Role-physical (79.5±31.0 vs 86.6±23.8; p=0.016), bodily pain (79.7±23.1 vs 87.1±17.7; p<0.001), general health (61.4±25.3 vs 73.1±22.1; p<0.001) and vitality (62.1±26.7 vs 70.8±22.3; p<0.001) were all significantly worse in DTC patients.

The same was true for social functioning (77.2±17.3 vs 84.8±13.2; p<0.001), role-emotional (74.3±23.6 vs 84.3±22.2; p<0.001), mental health (71.5±21.8 vs 81.7±20.3; p<0.001), and in the physical (PCS; 76.8±10.5 vs 83.3±9.9; p<0.001) and mental (MCS; 71.3±10.8 vs 80.4±10.1; p<0.001) component summaries.

Only physical functioning was comparable between patients and controls (p=0.694).

The presence of one or more comorbidities appeared to worsen SF-36 scores, resulting in significantly lower physical functioning (p<0.001). This trend was consistent across all domains of SF-36, except for social functioning, which was only significantly decreased by having at least two comorbidities (p<0.001).

This was further confirmed through multivariate analysis, which found that hypertension, diabetes and depression all correlated significantly with poor PCS scores, while hypertension, asthma and depression predicted lower MCS scores after 1 year.

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Most Read Articles
5 days ago
Ivermectin confers benefits in the treatment of COVID-19, with a recent study showing that its use helps reduce the risk of death especially in patients with severe pulmonary involvement.
4 days ago
Mental health comorbidities are common among patients with type 2 diabetes mellitus and may lead to worse outcomes, a recent study has found.
Roshini Claire Anthony, 13 Nov 2020

Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.

Yesterday
Vitamin D deficiency may be a contributing factor to the mortality rate among patients with the novel coronavirus disease (COVID-19), reports a new study.