Most Read Articles
22 Oct 2017
Drinking coffee, whether caffeinated or decaffeinated, is associated with a reduced risk of cardiovascular disease (CVD) and ischaemic heart disease (IHD) mortality in patients with a prior myocardial infarction (MI), according to a recent study.
01 Mar 2018
At a cardiology conference held in Hilton Kuala Lumpur, senior consultant cardiologist Dato’ Sri Dr Azhari Rosman spoke on the importance of non–high-density lipoprotein cholesterol (non–HDL-C) and combination therapy as a novel approach in the management of atherogenic dyslipidemia (AD).
23 Sep 2018
Supplementation with n−3 or omega-3 fatty acids does not help prevent serious vascular events in diabetic patients without evidence of cardiovascular disease at baseline, according to a study.
Roshini Claire Anthony, 11 Oct 2018

The risk of hospitalization due to heart failure was almost halved in patients with secondary mitral regurgitation who underwent transcatheter mitral valve repair plus medical therapy compared with those who underwent medical therapy alone, according to findings of the COAPT* trial.

Cognitive impairment tied to poor antihypertensive medication adherence among elderly adults

16 Aug 2018
When is enough really enough for patients in light of the growing shift towards polypharmacy?

Cognitive impairment appears to be a risk factor for poor adherence to antihypertensive medication among elderly adults without dementia, a recent study has shown.

The study included 20,071 elderly hypertensive adults without a history of dementia (60 years; 54.3 percent female), of whom 16.4 percent (n=3,297) were poorly compliant with antihypertensive medication.

Multivariate logistic regression analysis showed that low cognitive function was associated with poor medication adherence, such that each increment in the Prescreening Korean Dementia Screening Questionnaire was associated with a significant drop in the likelihood of good adherence (adjusted odds ratio [OR], 0.980; 96 percent CI, 0.961–0.999; p=0.042).

The presence of comorbidities, such as stroke (adjusted OR, 1.351; 1.151–1.585; p<0.001), coronary heart disease (adjusted OR, 1.501; 1.330–1.694; p<0.001), diabetes (adjusted OR, 1.639; 1.492–1.800; p<0.001) and dyslipidaemia (adjusted OR, 1.533; 1.388–1.693; p<0.001), was associated with better medication adherence.

In contrast, being diagnosed with cancer appeared to increase the likelihood of poor adherence (adjusted OR, 0.802; 0.686–0.939; p=0.006).

Sex (female vs male: adjusted OR, 0.929; 0.860–1.004; p=0.063) and scores in the Geriatric Depression Scale (adjusted OR, 0.988; 0.947–1.031; p=0.584) were unrelated to the risk of poor antihypertensive medication adherence.

“[C]linicians involved with geriatric care should monitor patients’ cognitive function and medication adherence. If a patient shows cognitive impairment, clinicians need to educate both the patient and caregiver about the importance of proper adherence. Clinicians should also consider interventions that optimize the cognitive function of elderly patients,” said researchers.

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Most Read Articles
22 Oct 2017
Drinking coffee, whether caffeinated or decaffeinated, is associated with a reduced risk of cardiovascular disease (CVD) and ischaemic heart disease (IHD) mortality in patients with a prior myocardial infarction (MI), according to a recent study.
01 Mar 2018
At a cardiology conference held in Hilton Kuala Lumpur, senior consultant cardiologist Dato’ Sri Dr Azhari Rosman spoke on the importance of non–high-density lipoprotein cholesterol (non–HDL-C) and combination therapy as a novel approach in the management of atherogenic dyslipidemia (AD).
23 Sep 2018
Supplementation with n−3 or omega-3 fatty acids does not help prevent serious vascular events in diabetic patients without evidence of cardiovascular disease at baseline, according to a study.
Roshini Claire Anthony, 11 Oct 2018

The risk of hospitalization due to heart failure was almost halved in patients with secondary mitral regurgitation who underwent transcatheter mitral valve repair plus medical therapy compared with those who underwent medical therapy alone, according to findings of the COAPT* trial.