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Coffee drinkers at low risk of incident chronic kidney disease

18 Apr 2018

Higher intake levels of coffee appear to be associated with reduced risk of developing chronic kidney disease (CKD), according to data from the Atherosclerosis Risk in Communities (ARIC) Study.

A total of 14,209 ARIC participants aged 45–64 years completed food frequency questionnaires to determine coffee consumption. Nineteen percent almost never drank coffee, 21 percent drank <1 cup/day, 25 percent drank 1 to <2 cups/day, 15 percent drank 2 to <3 cups/day and 19 percent drank 3 or more cups per day. Coffee intake levels per day were more likely to be higher in men, whites and current smokers.

During a median follow-up of 24 years, 3,845 individuals developed CKD (defined as estimated glomerular filtration rate <60 mL/min/1.73 m2, accompanied by ≥25-percent decline in estimated glomerular filtration rate, CKD-related hospitalization or death, or end-stage renal disease).

Compared with never-consumers, individuals with higher coffee intake levels had reduced risk of incident CKD (<1 cup/day: hazard ratio [HR], 0.90; 95 percent CI, 0.82–0.99; 1 to <2 cups/day: HR, 0.90; 0.82–0.99; 2 to <3 cups/day: HR, 0.87; 0.77-0.97; and ≥3 cups/day: HR, 0.84; 0.75–0.94).

Furthermore, each additional cup of coffee consumed per day lowered the risk of incident CKD by 3 percent (HR, 0.97; 0.95–0.99; p<0.001).

The present data support the 2015–2020 Dietary Guidelines for Americans, which recommend incorporating three to five cups of coffee per day into a healthy lifestyle, researchers said. [http://health.gov/dietaryguidelines/2015/guidelines/]

However, the study might be limited by self-reported coffee consumption and observational design. More studies are needed to evaluate whether coffee preparation methods, and sugar and milk added to coffee influence the renal protection obtained from consuming coffee, researchers added.

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Most Read Articles
Stephen Padilla, 2 days ago
Treatment with oral thrombopoietin receptor agonist eltrombopag leads to similar platelet counts in patients with chronic immune thrombocytopaenia (cITP) and persistent (per)ITP, according to the results of phase III (EXTEND) and IV studies presented at the 23rd Congress of the European Hematology Association (EHA 2018) held in Stockholm, Sweden.
Pearl Toh, 4 days ago
Lonely people were twice as likely to die from any cause than people who did not feel lonely, according to a study based on a national survey presented at the recent EuroHeartCare 2018 in Dublin, Ireland. Also, loneliness is associated with poorer patient-reported outcomes in terms of mental and physical health in patients with heart disease.
15 Jun 2018
Higher activity of plasma xanthine oxidase appears to be linked to insulin resistance and liver dysfunction among type 2 diabetes mellitus (T2DM) patients with metabolic syndrome (MetS), according to a recent Japan study.
Jairia Dela Cruz, 2 days ago
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