Most Read Articles
Roshini Claire Anthony, 06 Apr 2018

A better quality of diet during pregnancy is associated with lower neonatal adiposity and longer infant length at birth, according to findings from the GUSTO* study.

07 Apr 2018
Female cyclists do not have significantly worse urinary or sexual function compared with other athletes, a recent study has shown. However, other genitourinary conditions, such as saddle sores and genital numbness, are associated with cycling and may lead to sexual dysfunction.
Kavitha G. Shekar, 04 May 2016
Cannabis use during pregnancy increases the risk of maternal anaemia, and causes several adverse outcomes in infants like low birth weight (LBW), and increased neonatal intensive care unit (NICU) admissions, show findings of a systematic review and meta-analysis.
Pearl Toh, 07 Apr 2018
Managing asthma with short-acting β-agonists (SABAs) was associated with reduced fertility in women, while the use of inhaled corticosteroids (ICS) with or without long-acting β-agonists (LABAs) was not, according to the SCOPE* study.

Choline supplementation during pregnancy improves offspring information processing

09 Jan 2018

In pregnant mothers entering the third trimester, choline supplementation of approximately twice the recommended amount improves information processing in the offspring, a recent randomized, double-blind, controlled feeding study has shown.

Researchers randomized 26 women entering the third trimester of pregnancy to receive either 480 (n=13) or 930 (n=13) mg of choline supplements per day. Cognitive tests were performed on 24 offspring at ages 4, 7, 10, and 13 months.

In the adjusted regression analysis, the mean saccade reaction time (RT) of offspring of mothers who took the 930-mg choline supplements was 33.8 (95 percent CI, 2.7–54.9) ms faster than those of mothers who took the 480-mg supplements. The difference was statistically significant (p=0.03).

Age was also related with mean saccade RT, which declined significantly with increasing age (p<0.0001) in both treatment groups. Moreover, each additional week of gestation led to an 18.3-ms reduction in mean saccade RT.

To determine whether gestational age was a proxy for the duration of choline exposure, a new adjusted model was constructed, which showed a significant effect of days of exposure (p=0.02), but not gestational age (p=0.3), on RT. The resulting estimated effect of choline was 51.3 ms.

As expected, infants produced more predictive saccades for the predictable stimulus sequence than for the unpredictable baseline sequence (p<0.0001), but maternal choline intake had no significant impact (p=0.6).

“The results of this controlled-feeding trial reveal significantly faster saccade RT, a measure of information processing speed, among infants born to mothers consuming the higher level of choline intake throughout their third trimester,” said researchers.

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Most Read Articles
Roshini Claire Anthony, 06 Apr 2018

A better quality of diet during pregnancy is associated with lower neonatal adiposity and longer infant length at birth, according to findings from the GUSTO* study.

07 Apr 2018
Female cyclists do not have significantly worse urinary or sexual function compared with other athletes, a recent study has shown. However, other genitourinary conditions, such as saddle sores and genital numbness, are associated with cycling and may lead to sexual dysfunction.
Kavitha G. Shekar, 04 May 2016
Cannabis use during pregnancy increases the risk of maternal anaemia, and causes several adverse outcomes in infants like low birth weight (LBW), and increased neonatal intensive care unit (NICU) admissions, show findings of a systematic review and meta-analysis.
Pearl Toh, 07 Apr 2018
Managing asthma with short-acting β-agonists (SABAs) was associated with reduced fertility in women, while the use of inhaled corticosteroids (ICS) with or without long-acting β-agonists (LABAs) was not, according to the SCOPE* study.