Most Read Articles
01 Dec 2017
At a symposium during the 25th Congress of the Obstetrical and Gynaecological Society of Malaysia in Kuala Lumpur, Professor Susan Davis discussed the unique implications of women living decades beyond menopause, and how healthcare professionals can best manage menopausal symptoms in the short and long term.
Dr Joslyn Ngu, 04 Dec 2017

Making genetic testing mainstream, allows more patients to be tested, identifies more carriers and enables appropriate stratification of treatment and outcomes, says an expert.

Menelik MH Lee, MBBS, MRCOG, FHKCOG, FHKAM; Charles J Carter, MBChB, FRCS(urol); Tyrone T Carpenter, MBBS, BSc, MRCOG, MD, 01 Jun 2014

Laparoscopic partial cystectomy is established as the optimal treatment of full thickness bladder endometriosis. Complete excision of the lesion is essential however over excision risks unnecessary reduction in bladder volume and may risk ureteric obstruction. The following case demonstrates a new technique of cystoscopic mapping and laparoscopic resection of bladder endometriosis, allowing complete removal of the endometriotic nodule while sparing maximum bladder capacity and minimising risk of injury to the ureteric orifices.

20 Aug 2016
An elevated level of urinary nephrin (nephrinuria) may be associated with an increased risk of preeclampsia (PE), according to a study, suggesting that a certain cut-off can facilitate identification of women with greater PE risk.

Choline supplementation during pregnancy improves offspring information processing

09 Jan 2018

In pregnant mothers entering the third trimester, choline supplementation of approximately twice the recommended amount improves information processing in the offspring, a recent randomized, double-blind, controlled feeding study has shown.

Researchers randomized 26 women entering the third trimester of pregnancy to receive either 480 (n=13) or 930 (n=13) mg of choline supplements per day. Cognitive tests were performed on 24 offspring at ages 4, 7, 10, and 13 months.

In the adjusted regression analysis, the mean saccade reaction time (RT) of offspring of mothers who took the 930-mg choline supplements was 33.8 (95 percent CI, 2.7–54.9) ms faster than those of mothers who took the 480-mg supplements. The difference was statistically significant (p=0.03).

Age was also related with mean saccade RT, which declined significantly with increasing age (p<0.0001) in both treatment groups. Moreover, each additional week of gestation led to an 18.3-ms reduction in mean saccade RT.

To determine whether gestational age was a proxy for the duration of choline exposure, a new adjusted model was constructed, which showed a significant effect of days of exposure (p=0.02), but not gestational age (p=0.3), on RT. The resulting estimated effect of choline was 51.3 ms.

As expected, infants produced more predictive saccades for the predictable stimulus sequence than for the unpredictable baseline sequence (p<0.0001), but maternal choline intake had no significant impact (p=0.6).

“The results of this controlled-feeding trial reveal significantly faster saccade RT, a measure of information processing speed, among infants born to mothers consuming the higher level of choline intake throughout their third trimester,” said researchers.

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Most Read Articles
01 Dec 2017
At a symposium during the 25th Congress of the Obstetrical and Gynaecological Society of Malaysia in Kuala Lumpur, Professor Susan Davis discussed the unique implications of women living decades beyond menopause, and how healthcare professionals can best manage menopausal symptoms in the short and long term.
Dr Joslyn Ngu, 04 Dec 2017

Making genetic testing mainstream, allows more patients to be tested, identifies more carriers and enables appropriate stratification of treatment and outcomes, says an expert.

Menelik MH Lee, MBBS, MRCOG, FHKCOG, FHKAM; Charles J Carter, MBChB, FRCS(urol); Tyrone T Carpenter, MBBS, BSc, MRCOG, MD, 01 Jun 2014

Laparoscopic partial cystectomy is established as the optimal treatment of full thickness bladder endometriosis. Complete excision of the lesion is essential however over excision risks unnecessary reduction in bladder volume and may risk ureteric obstruction. The following case demonstrates a new technique of cystoscopic mapping and laparoscopic resection of bladder endometriosis, allowing complete removal of the endometriotic nodule while sparing maximum bladder capacity and minimising risk of injury to the ureteric orifices.

20 Aug 2016
An elevated level of urinary nephrin (nephrinuria) may be associated with an increased risk of preeclampsia (PE), according to a study, suggesting that a certain cut-off can facilitate identification of women with greater PE risk.