Most Read Articles
Elvira Manzano, 2 days ago
Monthly injections of the PCSK9* monoclonal antibody evolocumab effectively reduced plasma LDL-cholesterol (LDL-C), often referred to as the bad cholesterol, in teenagers with heterozygous familial hypercholesterolaemia (HeFH) already taking statins, with or without ezetimibe, the HAUSER-RCT has shown.
Jairia Dela Cruz, 2 days ago
For individual with type 2 diabetes, losing weight is everything when it comes to improving the metabolic function, and it matters little whether this is achieved by dieting or undergoing bariatric surgery, according to a small study.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
2 days ago
In patients with type 2 diabetes (T2D), postprandial hyperglycaemia and hypertriglyceridemia worsens survival outlook, finds a new study.

Chinese men with pleural tuberculosis at greater risk of empyema

05 Jan 2020

Tuberculosis empyema (TE) remains a common issue in China, especially among men, a recent study has shown.

Researchers conducted a retrospective cohort study on 474 patients with pleural tuberculosis (TB). Having grossly purulent pleural fluid was the basis for empyema identification. The primary study outcomes were factors predictive of TE.

Forty-two patients (mean age, 29.1±12.2 years; 90.5 percent male) were confirmed to have TE, resulting in an overall prevalence rate of 8.9 percent. The remaining 432 (91.1 percent; mean age, 36.3±18.5 years; 78.0 percent male) were established as non-TE comparators. More than half (51.3 percent) were smokers, and 71.1 percent had coughs, the most common symptom. Fevers were present in 70.7 percent and dyspnoea in 51.1 percent.

Multivariate logistic regression analysis identified being male as a strong and significant risk factor for developing TE in pleural TB patients (odds ratio [OR], 4.431, 95 percent confidence interval [CI], 1.411–13.919; p=0.011). Analysis was adjusted for pertinent confounders, such as age, comorbidity, symptoms and effusion sites.

Adenosine deaminase levels >88 U/L (OR, 3.367, 95 percent CI, 1.533–7.395; p=0.002) and white blood cell count >9.52 109/L (OR, 5.763; 95 percent CI, 2.473–13.431; p<0.001) also emerged as significant predictors of TE. In contrast, having pulmonary TB exerted a significant protective effect against TE (OR, 0.155, 95 percent CI, 0.072–0.336; p<0.001).

Important study limitations include its retrospective nature, the failure to take empyema stage into consideration and a single-centre design, which may limit its generalizability in broader populations, the researchers said. Further studies are required to validate the present findings.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Elvira Manzano, 2 days ago
Monthly injections of the PCSK9* monoclonal antibody evolocumab effectively reduced plasma LDL-cholesterol (LDL-C), often referred to as the bad cholesterol, in teenagers with heterozygous familial hypercholesterolaemia (HeFH) already taking statins, with or without ezetimibe, the HAUSER-RCT has shown.
Jairia Dela Cruz, 2 days ago
For individual with type 2 diabetes, losing weight is everything when it comes to improving the metabolic function, and it matters little whether this is achieved by dieting or undergoing bariatric surgery, according to a small study.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
2 days ago
In patients with type 2 diabetes (T2D), postprandial hyperglycaemia and hypertriglyceridemia worsens survival outlook, finds a new study.