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Chili pepper intake may reduce mortality risk in adults

27 Dec 2019

People who eat chili pepper regularly have a lower risk of total and cardiovascular disease (CVD) death independent of CVD risk factors or adherence to a Mediterranean diet, according to a study that involved a large Mediterranean population.

“Known biomarkers of CVD risk only marginally mediate the association of chili pepper intake with mortality,” the authors said.

The authors performed a longitudinal analysis on 22,811 men and women enrolled in the Moli-sani Study cohort (2005–2010). The European Prospective Investigation Into Cancer food frequency questionnaire was used to estimate chili pepper consumption, which was categorized as none/rare, up to 2 times/week, >2 to ≤4 times/week and >4 times/week.

Overall, 1,236 deaths were recorded over a median follow-up of 8.2 years. The risks of all-cause (hazard ratio [HR], 0.77, 95 percent confidence interval [CI], 0.66–0.90) and CVD mortality (HR, 0.39, 95 percent CI, 0.02–0.75) were reduced in participants in the regular (>4 times/week) intake group compared with those in the none/rare intake group.

Individuals who regularly consumed chili peppers also had lower risks of ischaemic heart disease (HR, 0.56, 95 percent CI, 0.35–0.87) and cerebrovascular (HR, 0.39, 95 percent CI, 0.20–0.75) deaths. A more robust association between chili pepper intake and total mortality was noted in those without hypertension (p-interaction=0.021).

Among known CVD biomarkers, only serum vitamin D marginally accounted for these associations.

“Chili pepper is a usual part of a traditional Mediterranean diet,” the authors noted.

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Most Read Articles
01 Nov 2019
Women with hypertensive disorders of pregnancy, especially pre-eclampsia, are at heightened risk of developing cardiovascular disorder and chronic hypertension, with the risk becoming apparent soon after pregnancy, a study has found.
Roshini Claire Anthony, 29 May 2019

Gestational diabetes and abnormal glucose levels in pregnancy, as determined with an oral glucose challenge test (OGCT) at 24–28 weeks gestation, could signal a future risk of cardiovascular disease (CVD)*, according to a recent study.

07 Jul 2019
Plasma creatinine kinase activity, measure during early pregnancy, influences blood pressure during pregnancy and contributes to severe gestational hypertension diagnosed before 34 weeks of gestation, according to a recent study. There is no association between creatinine kinase and other hypertensive disorders during pregnancy.
Pank Jit Sin, 16 Oct 2019
While a diagnosis of cancer is often met with concern and devastation, the same is barely true for heart failure. However, the mortality rate for those suffering from heart failure is worse than some common cancers, such as prostate and breast cancers.