Most Read Articles
01 Nov 2014
Current management of liver abscess is by intravenous antibiotics and percutaneous treatment. The efficacy of this management was assessed in this study.
05 Aug 2014
Clinical and laboratory data of acute kidney injury in patients with liver abscess were analyzed in this review.
08 Oct 2014
Anal fissure is an ulceration of the anoderm in the anal canal. Treatments usually do not target these causative factors. Recently, this review has been published giving an update on the management of anal fissure.
15 Feb 2012
This intervention review assessed the efficacy and morbidity of various anal fissure medical therapies in place for surgery.

Chicory-derived inulin may improve abdominal sensations, bowel motor function

30 Jul 2017

It appears that a daily dose of inulin is well tolerated by patients with gastrointestinal complaints, suggests a recent study, adding that inulin promotes bifidobacteria growth and may improve gut function.

Researchers performed a placebo-controlled, parallel, randomized, double-blind trial to determine the effect of a prebiotic chicory-derived inulin-type fructan on the tolerance of intestinal gas. Patients with abdominal symptoms and reduced tolerance of intestinal gas (selected by a pretest) were given either inulin (8 g/day; n=18) or maltodextrin as a placebo (8 g/day; n=18) for 4 weeks.

Researchers performed a gas challenge test (4 hours jejunal gas infusion at 12 mL/min while measuring abdominal symptoms and gas retention for 3 hours) before and at the end of the intervention phase. They also measured gastrointestinal symptoms and bowel habits using daily questionnaires for 1 weeks and faecal bifidobacteria counts before and at the end of the intervention.

Inulin, but not placebo, reduced gas retention by 22 percent during the gas challenge test (p=0.035), but the intergroup difference was not statistically significant (p=0.343). Furthermore, both inulin and placebo similarly reduced the perception of abdominal sensations in the gas challenges test by 52 and 43 percent, respectively.

At baseline, participants reported moderate gastrointestinal symptoms and normal bowel habits. These findings did not change in both groups during the intervention. Inulin resulted in a higher relative abundance of bifidobacteria counts (p=0.01 vs placebo).

According to researchers, individuals with gas-related complaints have impaired handling of intestinal gas loads.

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Most Read Articles
01 Nov 2014
Current management of liver abscess is by intravenous antibiotics and percutaneous treatment. The efficacy of this management was assessed in this study.
05 Aug 2014
Clinical and laboratory data of acute kidney injury in patients with liver abscess were analyzed in this review.
08 Oct 2014
Anal fissure is an ulceration of the anoderm in the anal canal. Treatments usually do not target these causative factors. Recently, this review has been published giving an update on the management of anal fissure.
15 Feb 2012
This intervention review assessed the efficacy and morbidity of various anal fissure medical therapies in place for surgery.