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Roshini Claire Anthony, 6 days ago

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Certain factors induce substantial, persisting risk of higher BMI in childhood

13 Jun 2018

Factors including parental body mass index (BMI), low socioeconomic position (SEP) and smoking during pregnancy exert a strong, persisting influence on childhood BMI and weight, regardless of birthweight and infancy BMI, study reports.

Researchers looked at family triads with available data on maternal, paternal and child BMI at ages 7 years (n=29,374) and 11 years (n=18,044) from the Danish National Birth Cohort. Data were obtained from maternal interviews and medical health examinations. Path analysis facilitated estimation of the direct and indirect effects of prenatal risk factors on childhood BMI z-scores (BMIz per unit score of the risk factor).

At age 7 years, the strongest direct effects on BMIz were produced by maternal and paternal BMI (0.19 and 0.14, respectively), low SEP (0.08), maternal smoking (0.12), and higher BMIz at 5 and 12 months (up to 0.19).

At age 11 years, similar effects were observed. However, the direct effects of BMIz at age 5 and 12 months were mediated through BMI at age 7 (0.62).

Results were similar for the risk of overweight at ages 7 and 11 years. In a child with average height and BMI, the sum of the direct effects could be translated to approximate absolute measures: 2.4 kg at 7 years and 5.7 kg at 11 years.

The findings show that certain factors produce a substantial and persisting risk of a higher BMI and of overweight in childhood, researchers said. These may play an important role in the fight against overweight and obesity in children.

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Most Read Articles
Roshini Claire Anthony, 6 days ago

A genotype-guided approach to warfarin dosing may result in fewer dose adjustments in Asian patients, according to a study from Singapore.

6 days ago
Patients with coronary artery disease (CAD) treated in a poor Southeast Asian setting appear to have far too high short-term and medium-term mortality rates, according to a study.
4 days ago
Heeding the advice to eat more vegetables has led to an increase in consumption above the Australian Dietary recommendation of ~375 g/day among overweight participants, a recent study has shown. Tomatoes are a common choice regardless of the time of year, but selections change over time.
21 Jul 2018
Although many patients with atopic dermatitis (AD) use antihistamines, no high-level evidence exists to prove that nonsedating antihistamines reduce itch in patients with AD or provide benefit in controlling AD symptoms, except perhaps sleep and AD comorbidities such as allergic rhinitis, according to a study.