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Certain factors induce substantial, persisting risk of higher BMI in childhood

13 Jun 2018

Factors including parental body mass index (BMI), low socioeconomic position (SEP) and smoking during pregnancy exert a strong, persisting influence on childhood BMI and weight, regardless of birthweight and infancy BMI, study reports.

Researchers looked at family triads with available data on maternal, paternal and child BMI at ages 7 years (n=29,374) and 11 years (n=18,044) from the Danish National Birth Cohort. Data were obtained from maternal interviews and medical health examinations. Path analysis facilitated estimation of the direct and indirect effects of prenatal risk factors on childhood BMI z-scores (BMIz per unit score of the risk factor).

At age 7 years, the strongest direct effects on BMIz were produced by maternal and paternal BMI (0.19 and 0.14, respectively), low SEP (0.08), maternal smoking (0.12), and higher BMIz at 5 and 12 months (up to 0.19).

At age 11 years, similar effects were observed. However, the direct effects of BMIz at age 5 and 12 months were mediated through BMI at age 7 (0.62).

Results were similar for the risk of overweight at ages 7 and 11 years. In a child with average height and BMI, the sum of the direct effects could be translated to approximate absolute measures: 2.4 kg at 7 years and 5.7 kg at 11 years.

The findings show that certain factors produce a substantial and persisting risk of a higher BMI and of overweight in childhood, researchers said. These may play an important role in the fight against overweight and obesity in children.

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Most Read Articles
Stephen Padilla, 2 days ago
Treatment with oral thrombopoietin receptor agonist eltrombopag leads to similar platelet counts in patients with chronic immune thrombocytopaenia (cITP) and persistent (per)ITP, according to the results of phase III (EXTEND) and IV studies presented at the 23rd Congress of the European Hematology Association (EHA 2018) held in Stockholm, Sweden.
Pearl Toh, 4 days ago
Lonely people were twice as likely to die from any cause than people who did not feel lonely, according to a study based on a national survey presented at the recent EuroHeartCare 2018 in Dublin, Ireland. Also, loneliness is associated with poorer patient-reported outcomes in terms of mental and physical health in patients with heart disease.
15 Jun 2018
Higher activity of plasma xanthine oxidase appears to be linked to insulin resistance and liver dysfunction among type 2 diabetes mellitus (T2DM) patients with metabolic syndrome (MetS), according to a recent Japan study.
Jairia Dela Cruz, 2 days ago
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