Most Read Articles
4 days ago
A recent study reports a mean growth rate of proximal aorta of about 0.1 mm/year in hypertensive patients with known aortic dilatation. In addition, those with increased rather than normal aortic z score have slower dilatation over time.
Tristan Manalac, 3 days ago
The coronavirus disease 2019 (COVID-19) appears to be more dangerous among cancer patients, who tend suffer more severe complications and faster disease progression, according to a new study.
Roshini Claire Anthony, 2 days ago

Among patients with nonvalvular atrial fibrillation (AF), treatment with apixaban was associated with a lower rate of ischaemic stroke, systemic embolism, and major bleeding compared with rivaroxaban, according to a large study assessing patients in routine care.

20 hours ago
Exposure to sunlight appears to increase the risk of vulvovaginal candidiasis (VVC) development, reveals a recent study in an African population.

Catheter ablation cuts long-term dementia risk in AF patients

24 Mar 2020

Catheter ablation in patients with atrial fibrillation (AF) appears to decrease the risk of dementia in the long run, a new study has found.

The study included 787 AF patients (mean age, 54.1±11.5 years; 70.1 percent male) who underwent catheter ablation. The new onset of dementia was monitored over a mean follow-up duration of 9.0±2.6 years. The participants were compared against two other cohorts: AF patients who did not undergo catheter ablation (n=787) and no-AF controls (n=770).

Over the study duration, 139 new cases of dementia were reported. The incidence rate was lower among AF patients who received catheter ablation relative to both the no-ablation and control groups (4.78 vs 6.92 and 6.00 per 1,000 patient-years).

Over the same time span, 732 AF-related hospitalizations were reported. Incidence was similarly lower in AF patients with vs without catheter ablation (68.7 vs 81.1 per 1,000 patient-years).

Adjusted multivariable Cox proportional hazard regression analyses confirmed that AF patients who had not undergone catheter ablation were at a significantly greater risk of dementia than controls (adjusted hazard ratio [HR], 1.71; p=0.047), while AF patients with vs without ablation were less likely to develop dementia in the long run. Risk comparisons between ablation patients and controls were null (p=0.93).

In addition, AF-related hospitalizations were less likely to occur in AF patients who had vs had not undergone catheter ablation (HR, 0.72; p<0.05).

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
4 days ago
A recent study reports a mean growth rate of proximal aorta of about 0.1 mm/year in hypertensive patients with known aortic dilatation. In addition, those with increased rather than normal aortic z score have slower dilatation over time.
Tristan Manalac, 3 days ago
The coronavirus disease 2019 (COVID-19) appears to be more dangerous among cancer patients, who tend suffer more severe complications and faster disease progression, according to a new study.
Roshini Claire Anthony, 2 days ago

Among patients with nonvalvular atrial fibrillation (AF), treatment with apixaban was associated with a lower rate of ischaemic stroke, systemic embolism, and major bleeding compared with rivaroxaban, according to a large study assessing patients in routine care.

20 hours ago
Exposure to sunlight appears to increase the risk of vulvovaginal candidiasis (VVC) development, reveals a recent study in an African population.