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Jairia Dela Cruz, 3 days ago
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Cancer outcomes affected by mental health

11 Dec 2019

Mental health issues worsen clinical outcomes in cancer patients, a new study has shown. This effect appears to scale with the severity of the mental health problem.

The study included 1,652 cancer patients whose medical records were reviewed for study outcomes, such as delays in initiating the cancer treatment, hospital admissions and 12-month all-cause mortality. The majority (n=1,402; mean age, 63.25±15.02 years; 52.3 percent female) had no mental health issues, while 139 (mean age, 66.34±13.44 years; 67.6 percent female) and 111 patients (mean age, 65.21±14.69 years; 60.4 percent female) had moderate and serious mental health problems, respectively.

Patients with moderate and serious mental health issues were more likely to have comorbidities, while more participants with serious problems presented with advanced malignancies. Those with severe mental health issues also had greater mortality risks.

Logistic regression analysis identified mental health issues as significant predictors of worse clinical outcomes. For instance, patients with serious problems were more likely to need hospital admissions (odds ratio [OR], 1.62, 95 percent confidence interval [CI], 1.06–2.49; p=0.027) and to die within 12 months (OR, 0.55, 95 percent CI, 0.99–3.03; p=0.056) than their counterparts without such issues.

No such effect was reported for moderate mental health issues (hospital admissions: OR, 1.43, 95 percent CI, 0.98–2.09; p=0.65; 12-month mortality: OR, 0.77, 95 percent CI, 0.42–1.40; p=0.386).

Further studies are needed to better understand the complex interactions between mental health and cancer, said researchers. In turn, these may lead to better care for these patients.

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Most Read Articles
Jairia Dela Cruz, 3 days ago
Metabolic and bariatric surgery (MBS) leads to large and sustained reductions in, and even reversal of, multiple risk factors for future joint disease in adolescents with severe obesity and musculoskeletal pain, according to data from the Teen Longitudinal Assessment of Bariatric Surgery study.
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
Pearl Toh, 6 days ago
Obeticholic acid significantly improves fibrosis and disease activity in patients with nonalcoholic steatohepatitis (NASH), a chronic liver disease currently with no approved therapy, according to an interim analysis of the landmark REGENERATE* study.