Most Read Articles
Saras Ramiya, 15 Apr 2017
After being introduced to Malaysia 10 years ago, Bio-Oil has established itself as a staple skincare brand.
Jenny Ng, 05 Aug 2015
Concerns emerge over combining antidepressants with non-steroidal anti-inflammatory drugs (NSAIDs) as a study shows an increased risk of intracranial haemorrhage (ICH) in these patients. 
Debra Kennedy, 01 Jun 2014

Pregnant women do not need to suffer unnecessary pain or potentially dangerous fever for fear of their taking medications that may be harmful to their unborn baby. Healthcare providers should be confident when prescribing appropriate treatment to such women during pregnancy.

Harriet Pugsley, MB ChB, MRCOG; Judith Moore, MRCOG, 01 Aug 2013

Most women presenting with complications in early pregnancy are assessed, diagnosed and managed at early pregnancy assessment units (EPAUs). These units aim to provide thorough assessments, access to specialist investigations (scan, human chorionic gonadotrophin [hCG]), a rapid turnaround of results, and co-ordination of further management.

Canagliflozin decreases serum uric acid level in diabetic patients with or without baseline hyperuricaemia

Fiel Soliven
01 Apr 2015
Hyperuricaemia is associated with numerous diseases; thus, decreasing serum uric acid may be beneficial for type 2 diabetes mellitus (T2DM) patients. The effects canagliflozin on serum acid levels of T2DM patients and a subset who have hyperuricaemia were assessed in this review article.

The present post hoc analysis of four placebo-controlled phase III trials revealed that canagliflozin is connected to an approximately 13 percent decrease in serum acid compared to placebo. Also, 23.5 and 32.4 percent of hyperuricaemic patients who received canagliflozin 100 and 300 mg, respectively, attained serum uric acid level of < 360 µmol/L (~ 6 mg/dL) compared to the 3.1 percent with placebo. The occurrence of kidney stones and gout were also low and similar throughout the groups.

Canagliflozin was concluded to lower serum uric acid in T2DM patients, including those who have hyperuricaemia initially.
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Most Read Articles
Saras Ramiya, 15 Apr 2017
After being introduced to Malaysia 10 years ago, Bio-Oil has established itself as a staple skincare brand.
Jenny Ng, 05 Aug 2015
Concerns emerge over combining antidepressants with non-steroidal anti-inflammatory drugs (NSAIDs) as a study shows an increased risk of intracranial haemorrhage (ICH) in these patients. 
Debra Kennedy, 01 Jun 2014

Pregnant women do not need to suffer unnecessary pain or potentially dangerous fever for fear of their taking medications that may be harmful to their unborn baby. Healthcare providers should be confident when prescribing appropriate treatment to such women during pregnancy.

Harriet Pugsley, MB ChB, MRCOG; Judith Moore, MRCOG, 01 Aug 2013

Most women presenting with complications in early pregnancy are assessed, diagnosed and managed at early pregnancy assessment units (EPAUs). These units aim to provide thorough assessments, access to specialist investigations (scan, human chorionic gonadotrophin [hCG]), a rapid turnaround of results, and co-ordination of further management.