Most Read Articles
01 Nov 2019
Women with hypertensive disorders of pregnancy, especially pre-eclampsia, are at heightened risk of developing cardiovascular disorder and chronic hypertension, with the risk becoming apparent soon after pregnancy, a study has found.
Roshini Claire Anthony, 29 May 2019

Gestational diabetes and abnormal glucose levels in pregnancy, as determined with an oral glucose challenge test (OGCT) at 24–28 weeks gestation, could signal a future risk of cardiovascular disease (CVD)*, according to a recent study.

07 Jul 2019
Plasma creatinine kinase activity, measure during early pregnancy, influences blood pressure during pregnancy and contributes to severe gestational hypertension diagnosed before 34 weeks of gestation, according to a recent study. There is no association between creatinine kinase and other hypertensive disorders during pregnancy.
Pank Jit Sin, 16 Oct 2019
While a diagnosis of cancer is often met with concern and devastation, the same is barely true for heart failure. However, the mortality rate for those suffering from heart failure is worse than some common cancers, such as prostate and breast cancers. 

CABG outperforms PCI in diabetics with multivessel disease

20 Oct 2019

Coronary artery bypass graft (CABG) leads to better long-term survival than percutaneous coronary intervention (PCI) in unselected type 2 diabetes patients, a recent study has found.

Researchers enrolled 430 diabetes mellitus patients with multivessel disease determined through angiographic screening. At a median of 6 years, the overall rate for all-cause mortality was 25 percent. This was significantly greater in those who underwent CABG vs PCI or who had no revascularization (16 percent vs 26 percent and 33 percent; p=0.009).

Those who received CABG also had the lowest rate of nonfatal myocardial infarction relative to other procedures (p=0.016). The same was true for the composite endpoint of death, stroke and myocardial infarction (p<0.001).

Multivariable analysis further showed that not undergoing CABG was a significant risk factor for late mortality, as were older age and hypertension. In comparison, presenting with acute coronary syndrome and triple vessel disease were significantly associated with greater risks of late myocardial infarction.

The composite endpoint, on the other hand, was correlated triple vessel disease, acute coronary syndrome and not undergoing any revascularization procedures.

Subsequent propensity analyses found that those treated with PCI showed significantly higher rates of mortality (hazard ratio [HR], 1.94, 95 percent CI, 1.02–3.70; p=0.045), myocardial infarction (HR, 2.87, 1.12–7.31; p=0.028) and of the composite outcome (HR, 1.80, 1.11–2.92; p=0.017) than their CABG counterparts. These trends held up in multivariable Cox regression analysis.

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Most Read Articles
01 Nov 2019
Women with hypertensive disorders of pregnancy, especially pre-eclampsia, are at heightened risk of developing cardiovascular disorder and chronic hypertension, with the risk becoming apparent soon after pregnancy, a study has found.
Roshini Claire Anthony, 29 May 2019

Gestational diabetes and abnormal glucose levels in pregnancy, as determined with an oral glucose challenge test (OGCT) at 24–28 weeks gestation, could signal a future risk of cardiovascular disease (CVD)*, according to a recent study.

07 Jul 2019
Plasma creatinine kinase activity, measure during early pregnancy, influences blood pressure during pregnancy and contributes to severe gestational hypertension diagnosed before 34 weeks of gestation, according to a recent study. There is no association between creatinine kinase and other hypertensive disorders during pregnancy.
Pank Jit Sin, 16 Oct 2019
While a diagnosis of cancer is often met with concern and devastation, the same is barely true for heart failure. However, the mortality rate for those suffering from heart failure is worse than some common cancers, such as prostate and breast cancers.