Most Read Articles
4 days ago
Ivermectin confers benefits in the treatment of COVID-19, with a recent study showing that its use helps reduce the risk of death especially in patients with severe pulmonary involvement.
3 days ago
Mental health comorbidities are common among patients with type 2 diabetes mellitus and may lead to worse outcomes, a recent study has found.
Roshini Claire Anthony, 13 Nov 2020

Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.

Tristan Manalac, 18 Nov 2020
The substitution of isoleucine to leucine at amino acid 97 (I97L) in the core region of the hepatitis B virus (HBV) seems to reduce its potency, decreasing the efficiency of both infection and the synthesis of the virus’ covalently closed circular (ccc) DNA, reports a new study presented at The Liver Meeting Digital Experience by the American Association for the Study of Liver Diseases (AASLD 2020).

Brown rice, wheat diets ease constipation among women

16 Nov 2020

Brown rice-based (BRD) and wheat-based (WD) diets improve bowel movement and total colon transit time (TCTT) among women with functional constipation, finds a recent Korea study. Diets reliant on white rice (WRD), on the other hand, show no such effect.

Researchers randomly assigned 39 young women (mean age, 21.8±2.0 years) with functional constipation to a BRD, WRD, or WD, at a 1:1:1 ratio, for a period of 4 weeks. Participants were given three meals a day (at 7 AM, 12 noon, and 6 PM), through a 14-day menu cycle based on an estimated daily energy need of 2,100 kcal. The primary outcome measure was TCTT.

Women assigned to the BRD intervention saw a decrease in TCTT in the total colon (p=0.032), driven particularly by a similar change in the left colon (p=0.030). Both the BRD (p=0.028) and WD (p=0.022) groups saw significant reductions in TCTT relative to the WRD group.

Similarly, stool frequency in the BRD group jumped from 3.4±1.1 times per week before the trial to 5.0±1.1 times per week after (p<0.002). A similar and statistical change was also seen in the WD arm, though to a slightly attenuated degree (2.8±1.0 to 3.9±1.3 times per week; p<0.012). There was also a tendency toward increasing bowel frequency, though it failed to reach significance.

These bowel benefits came with no safety concerns. The researchers documented no subjective or objective adverse events, nor were there any substantial changes in vital signs and in physical and diagnostic exams. Laboratory markers all likewise stayed within normal ranges.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
4 days ago
Ivermectin confers benefits in the treatment of COVID-19, with a recent study showing that its use helps reduce the risk of death especially in patients with severe pulmonary involvement.
3 days ago
Mental health comorbidities are common among patients with type 2 diabetes mellitus and may lead to worse outcomes, a recent study has found.
Roshini Claire Anthony, 13 Nov 2020

Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.

Tristan Manalac, 18 Nov 2020
The substitution of isoleucine to leucine at amino acid 97 (I97L) in the core region of the hepatitis B virus (HBV) seems to reduce its potency, decreasing the efficiency of both infection and the synthesis of the virus’ covalently closed circular (ccc) DNA, reports a new study presented at The Liver Meeting Digital Experience by the American Association for the Study of Liver Diseases (AASLD 2020).