Most Read Articles
Naomi Rodrig, 15 Jun 2016
An interim analysis from the multinational phase III CASTOR trial, presented recently at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting, showed that adding daratumumab to the standard two-drug regimen of bortezomib and dexamethasone markedly improved outcomes of patients with recurrent or refractory multiple myeloma.

Brentuximab vedotin: A CD30-positive targeted therapy in a heavily pretreated relapsed or refractory Hodgkin lymphoma

19 Sep 2018
Kanker darah, seperti leukemia, Hodgkin lymphona, non-Hodgkin lymphoma dan multiple myeloma
Brentuximab vedotin (ADCETRIS®; Takeda Pharmaceuticals) is an antibody-drug conjugate that selectively delivers monomethyl auristatin E, a very potent antimicrotubule agent,into CD30-positive tumour cells, leading to the disruption of the microtubule network. This results in cell cycle arrest and apoptotic death of the CD30-positive cells, making brentuximab vedotin a promising anticancer agent.6,7

Related MIMS Drugs

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Oncology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Naomi Rodrig, 15 Jun 2016
An interim analysis from the multinational phase III CASTOR trial, presented recently at the 2016 American Society of Clinical Oncology (ASCO) Annual Meeting, showed that adding daratumumab to the standard two-drug regimen of bortezomib and dexamethasone markedly improved outcomes of patients with recurrent or refractory multiple myeloma.