Most Read Articles
Dr Margaret Shi, 02 Jan 2020

Tivozanib as third- or fourth-line therapy improves progression-free survival (PFS) compared with sorafenib in patients with metastatic renal cell carcinoma (mRCC) who have received ≥2 previous systemic treatments, according to results of the phase III, randomized, controlled TIVO-3 trial.

Brentuximab vedotin: A CD30-positive targeted therapy in a heavily pretreated relapsed or refractory Hodgkin lymphoma

19 Sep 2018
Brentuximab vedotin (ADCETRIS®; Takeda Pharmaceuticals) is an antibody-drug conjugate that selectively delivers monomethyl auristatin E, a very potent antimicrotubule agent,into CD30-positive tumour cells, leading to the disruption of the microtubule network. This results in cell cycle arrest and apoptotic death of the CD30-positive cells, making brentuximab vedotin a promising anticancer agent.6,7

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Most Read Articles
Dr Margaret Shi, 02 Jan 2020

Tivozanib as third- or fourth-line therapy improves progression-free survival (PFS) compared with sorafenib in patients with metastatic renal cell carcinoma (mRCC) who have received ≥2 previous systemic treatments, according to results of the phase III, randomized, controlled TIVO-3 trial.