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Pearl Toh, 12 Sep 2020
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Breathing cleaner air indoors promotes healthy blood pressure levels

20 Jun 2020

Using an air filtration system facilitates improved air quality around the house by reducing indoor exposures to particulate matter, which, in turn, exerts a favourable effect on systolic blood pressure (SBP), a study has found.

Researchers conducted a systematic review of randomized controlled trials evaluating the effects of using personal air cleaners (PACs), including high-efficiency particulate air filters and electrostatic precipitators, as opposed to sham filtration. Outcomes included PM2.5 exposure and SBP.

Ten studies involving a total of 604 participants met the inclusion criteria. The PM2.5 concentrations at baseline were categorized using the WHO criteria. Two studies reported low air pollution exposure levels (35 μg/m3), while one study was classified as indeterminate as PM2.5 was not quantified.

Median study duration was 9 days in nine studies, while the remaining study lasted 12 months. In general, PAC use yielded an absolute reduction in PM2.5 of 20.9 μg/m3, which translated to a relative reduction of 55.9 percent.

Over a median follow-up of 13.5 days, PACs were associated with a significant reduction in mean SBP of around 4 mm Hg (−3.94 mm Hg; p=0.01) and a nonsignificant decrease in mean diastolic blood pressure (−0.95 mm Hg; p=0.32).

Subgroup analyses did not detect heterogeneity of effect by age, level of particulate exposure, or study duration.

Given the variation in study design, more studies are needed to validate the present data and better quantify the observed benefits for systolic BP associated with the use of personal air cleaners.

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Most Read Articles
Pearl Toh, 12 Sep 2020
Early initiation of rhythm-control therapy led to a significantly reduced risk of major adverse cardiovascular (CV) outcomes compared with usual care (typically rate control) in patients with newly diagnosed atrial fibrillation (AF) at risk of stroke, reveals the EAST-AFNET 4* trial presented at ESC 2020.
Audrey Abella, 16 Sep 2020
The final results of EVAPORATE* reinforce the plaque-regressing potential of icosapent ethyl (IPE) in patients on statins for elevated triglycerides.