Most Read Articles
2 days ago
Dairy consumption during adolescence or early adulthood does not appear to be associated with the overall risk of breast cancer, although results vary by hormone receptor status of tumours, a study has shown. Specifically, dairy intake is linked to higher ER–/PR– and lower ER+/PR+ cancer risk.
Roshini Claire Anthony, 5 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

3 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
4 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.

Breastfeeding helps prevent endometriosis

Stephen Padilla
04 Sep 2017

An inverse relationship exists between breastfeeding and risk of incident endometriosis among women who experienced at least one pregnancy that lasted at least 6 months, according to a recent study. Postpartum amenorrhoea partially, but not fully, influences such association, suggesting that breastfeeding may affect the risk of endometriosis both through amenorrhoea and other mechanisms.

“The strong inverse relation we found between duration of breastfeeding and risk might have important clinical implications for advising women to modify their risk profile for endometriosis. Our findings lend support to the body of public health and policy literature that advocates for the promotion of breastfeeding,” researchers said.

“All women should be counseled regarding the health benefits of breastfeeding for both the mother and child, systems level policy changes should be implemented to encourage breastfeeding, and future research should investigate the benefit of breastfeeding among women diagnosed with endometriosis for symptom control,” they added.

Total and exclusive breastfeeding significantly correlated with decreased risk of endometriosis. There were 453 endometriosis cases per 100,000 person-years among women who reported a lifetime total length of breastfeeding of <1 month compared with 184 cases per 100,000 person-years in women who reported a lifetime total of ≥36 months of breastfeeding. [BMJ 2017;358:j3778]

Each additional 3 months of total breastfeeding per pregnancy resulted in an 8-percent lower risk of endometriosis (hazard ratio [HR], 0.92; 95 percent CI, 0.90 to 0.94; p<0.001 for trend), and each additional 3 months of exclusive breastfeeding led to a 14-percent lower risk (HR, 0.86; 0.81 to 0.90; p<0.001 for trend).

Breastfeeding for ≥36 months in total across women’s reproductive lifetime resulted in a 40-percent reduced risk of endometriosis compared with those who never breastfed (HR, 0.60; 0.50 to 0.72). This protective association with breastfeeding was strongest among women who gave birth within the past 5 years (p=0.04 for interaction).

Furthermore, postpartum amenorrhoea partially influenced the association between endometriosis and total (% mediated, 34 percent; 15 to 59 percent) and exclusive (% mediated, 57 percent; 27 to 82 percent) breastfeeding.

“Our findings confirm previous reports of an inverse relation between breastfeeding and risk of endometriosis. In previous research within our cohort, with 6 years of follow-up and 448 incident cases, we reported a significant relation between a one-time measure of lifetime duration of breastfeeding and endometriosis (p=0.008 for linear trend). [Obstet Gynecol 2004;358:965-74; Environ Res 2007;358:121-9]

In this prospective cohort study, the investigators identified a total of 72,394 women who reported having one or more pregnancies that lasted at least 6 months. Of these, 3,296 had laparoscopically confirmed endometriosis. For each pregnancy, women reported duration of total breastfeeding, exclusive breastfeeding and postpartum amenorrhoea.

“Endometriosis is a chronic disease with no known cure and debilitating symptoms. At present, few modifiable risk factors are known to prevent its occurrence. Future research should investigate breastfeeding as a mechanism for mitigation of symptoms among women with a diagnosis of endometriosis,” according to researchers.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
2 days ago
Dairy consumption during adolescence or early adulthood does not appear to be associated with the overall risk of breast cancer, although results vary by hormone receptor status of tumours, a study has shown. Specifically, dairy intake is linked to higher ER–/PR– and lower ER+/PR+ cancer risk.
Roshini Claire Anthony, 5 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

3 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
4 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.