Most Read Articles
Pearl Toh, 10 Oct 2019
Adding a LAMA* to the double combination therapy of ICS** plus LABA*** in a single inhaler improves lung function and reduces exacerbations in patients whose asthma is inadequately controlled with the combination treatment, according to the TRIMARAN and TRIGGER# studies presented at ERS 2019.
4 days ago
Eating alone may help in weight management as findings of a recent study suggest that eating with friends lead to higher food intake.
Tristan Manalac, 3 days ago
A digital-first approach, iConnect, allows patients to have greater access to services and guidance and enables healthcare providers to deliver much better postdischarge care, according to Lim Cher Wee, chief operating officer of the Ministry of Health, Office for Healthcare Transformation of Singapore, in his presentation at the recently concluded AsiaPac19 Conference & Exhibition of the Healthcare Information and Management Systems Society (HIMSS 2019).
Jairia Dela Cruz, 3 days ago
Toileting behaviours such as convenience and delayed voiding, straining to void, and position preference are strongly associated with overactive bladder (OAB) symptoms in women, according to a study.

Breast cancer screening may impair quality of life of high-risk women

12 Jul 2019

Health utility scores, an overall indicator of health-related quality of life (HRQoL), appear to be lower among participants of breast cancer screening programmes, though the difference may not be clinically significant, reports a new study.

The study included 2,378 women at high risk of breast cancer (HR-BC; mean age, 51.55±7.32 years) whose HRQoLs were measured using the three-level EuroQol-five-Dimensions (EQ-5D-3L). A total of 2,378 general population controls (mean age, 51.63±7.37 years) were also included.

The mean utility scores in the general population and HR-BC cohorts were 0.953 and 0.937, respectively. The between-group difference was statistically significant (p<0.001), though its magnitude of 0.016 fell short of the minimally important difference threshold value.

This difference was driven mainly by the anxiety/depression (18.8 percent vs 15.5 percent; p<0.001) and pain/discomfort (28.3 percent vs 22.1 percent; p<0.001) domains of the EQ-5D-3L. Specifically, these symptoms were more frequently reported by the HR-BC participants.

Multivariate regression analysis found that participants who were older at the time of the survey tended to have lower utility scores. For instance, relative to those who were younger than 45 years, women aged 50–54 (β, –0.018, 95 percent CI, –0.029 to –0.005; p=0.004), 55–59 (β, –0.032, –0.045 to –0.018; p<0.001) and 60–64 (β, –0.027, –0.041 to –0.012; p<0.001) years had lower utility scores.

“Although the observed HRQoL reduction was clinically trivial for HR-BC participants, BC screening may negatively impact emotional well-being such as increasing anxiety/depression,” said researchers, noting that psychological surveillance and counselling, where necessary, may be helpful in this population.

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Most Read Articles
Pearl Toh, 10 Oct 2019
Adding a LAMA* to the double combination therapy of ICS** plus LABA*** in a single inhaler improves lung function and reduces exacerbations in patients whose asthma is inadequately controlled with the combination treatment, according to the TRIMARAN and TRIGGER# studies presented at ERS 2019.
4 days ago
Eating alone may help in weight management as findings of a recent study suggest that eating with friends lead to higher food intake.
Tristan Manalac, 3 days ago
A digital-first approach, iConnect, allows patients to have greater access to services and guidance and enables healthcare providers to deliver much better postdischarge care, according to Lim Cher Wee, chief operating officer of the Ministry of Health, Office for Healthcare Transformation of Singapore, in his presentation at the recently concluded AsiaPac19 Conference & Exhibition of the Healthcare Information and Management Systems Society (HIMSS 2019).
Jairia Dela Cruz, 3 days ago
Toileting behaviours such as convenience and delayed voiding, straining to void, and position preference are strongly associated with overactive bladder (OAB) symptoms in women, according to a study.