Most Read Articles
02 Nov 2019
Treatment with the selective serotonin reuptake inhibitor escitalopram may confer beneficial effects on neuroticism, possibly by inducing reduction in anxiety, a recent study has shown.
05 Nov 2019
Low total cholesterol levels appear to carry increased major adverse cardiovascular events (MACE) hazard in older men without ischaemic heart disease (IHD) and not receiving statin therapy but not to those on statins, according to data from the CHAMP (Concord Health and Ageing in Men Project) cohort.
5 days ago
Maribavir 400 mg twice daily appears to have comparable efficacy to valganciclovir at clearing cytomegalovirus viraemia in transplant recipients, a study has found.
4 days ago
Individuals with and without gout appear to have a similar risk of developing colorectal cancer, suggesting that gout does not contribute to a risk increase, a study has found.

Brain size tied to physical growth in preemies

02 Nov 2019

In preterm infants, the weight and body mass index (BMI) gain from birth to term age are both correlated with brain size, a recent study has found.

 The study included 62 preterm infants (born <33 weeks of gestation; 56 percent male) whose weights and lengths were measured at birth. Air displacement plethysmography was performed at term to determine body composition, while magnetic resonance imaging was used to quantify brain size.

Cross-sectionally, researchers found links between brain size and body composition. Each additional 100 mg of lean mass, for instance, was correlated with a 0.62-mm increase in bifrontal diameter (BFD) and a 0.70-mm larger biparietal diameter (BPD). A corresponding 0.26-mm increase in transverse cerebral diameter (TCD) was also reported.

Brain size also shared longitudinal associations with physical growth. From birth to term-equivalent age, each additional Z-score gain in weight was correlated with a 2.1-mm increase in BFD, a 2.6-mm larger BPD and a 1.3-mm increment in TCD. A similar and strongly positive trend was reported for BMI in relation to brain size, though at lower magnitudes.

In contrast, linear growth, expressed as the change in Z-scores of body length, did not share a discernible relationship with brain size.

“It is not yet known whether interventions that improve lean mass accrual could also improve brain growth and neurodevelopment,” said researchers. “Nevertheless, body composition is an attractive biomarker of brain growth in preterm infants.”

Editor's Recommendations
Most Read Articles
02 Nov 2019
Treatment with the selective serotonin reuptake inhibitor escitalopram may confer beneficial effects on neuroticism, possibly by inducing reduction in anxiety, a recent study has shown.
05 Nov 2019
Low total cholesterol levels appear to carry increased major adverse cardiovascular events (MACE) hazard in older men without ischaemic heart disease (IHD) and not receiving statin therapy but not to those on statins, according to data from the CHAMP (Concord Health and Ageing in Men Project) cohort.
5 days ago
Maribavir 400 mg twice daily appears to have comparable efficacy to valganciclovir at clearing cytomegalovirus viraemia in transplant recipients, a study has found.
4 days ago
Individuals with and without gout appear to have a similar risk of developing colorectal cancer, suggesting that gout does not contribute to a risk increase, a study has found.