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01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Jairia Dela Cruz, 5 days ago
For inflammatory bowel disease (IBD) patients, smoking cigarettes or just being exposed to secondhand smoke raises the risk of developing colorectal neoplasia, a study has found.
Jairia Dela Cruz, Yesterday
Spending too much time sitting cannot be good for the body, and rising to one's feet breaks up such a behaviour and yields small, but meaningful, reductions in certain cardiovascular disease (CVD) risk factors, according to the results of a meta-analysis.

BMI shows no impact in outcomes of urinary tract reconstruction in teens

08 Dec 2019

Obesity does not seem to affect 30-day morbidity outcomes in children and adolescents undergoing continent urinary tract reconstruction, a recent study has shown.

Researchers conducted a retrospective analysis of 182 continent reconstruction procedures performed on paediatric and adolescent patients who were, at most, 20 years of age. Primary outcomes included the duration of admission to intensive care or to the hospital, as well as complications and the need for readmissions within 30 days.

Majority of the participants (62.6 percent; n=114) were of normal body mass index (BMI), while 15.4 percent (n=28) and 13.2 percent (n=24) were obese and overweight, respectively. More than a quarter (28.6 percent; n=52) had any level of obesity, as determined by age-appropriate BMI z-scores.

Overall, participants had to spend a median of 1.0 day in intensive care and 11.0 days hospitalized. Length of hospitalization was shortest in the underweight group (10.5 days), but no significant effect was reported according to BMI groups. Median intensive care stay was the same across BMI categories.

The same was true for the overall rate of 30-day readmissions (14.3 percent; n=26). This was highest among those with normal (18.4 percent) and obese (10.7 percent) BMI and lowest in the underweight group, where no such case was reported. Among-group discrepancies failed to meet significance (p=0.06).

Complications likewise occurred at similar frequencies among BMI categories: underweight (31.3 percent), normal (45.6 percent), overweight (33.3 percent) and obese (39.3 percent; p=0.53). Disaggregating into the different types of complications did not change the principal findings.

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Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Jairia Dela Cruz, 5 days ago
For inflammatory bowel disease (IBD) patients, smoking cigarettes or just being exposed to secondhand smoke raises the risk of developing colorectal neoplasia, a study has found.
Jairia Dela Cruz, Yesterday
Spending too much time sitting cannot be good for the body, and rising to one's feet breaks up such a behaviour and yields small, but meaningful, reductions in certain cardiovascular disease (CVD) risk factors, according to the results of a meta-analysis.