Most Read Articles
06 Jul 2020
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Jairia Dela Cruz, 06 Jul 2020
Following vegan and vegetarian diets, which offer plenty of what is good for health, has been reported to have a downside: an increased risk of depression and anxiety, especially for younger adults.
Pearl Toh, 29 Jun 2020
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
Roshini Claire Anthony, 5 days ago

Upadacitinib may be a suitable treatment for patients with active psoriatic arthritis (PsA) who have insufficient response to non-biologic disease-modifying anti-rheumatic drugs (non-bDMARDs), according to results of the phase III SELECT-PsA-1* trial presented at EULAR 2020.

BMI, CRP level tied to extraintestinal manifestations in children with IBD

06 Jun 2020

Extraintestinal manifestations (EIMs) in children with inflammatory bowel disease (IBD) are associated with body mass index (BMI) in the lower or upper quartile, lower haemoglobin level, and higher C-reactive protein (CRP) level, among others, a recent study has shown.

“Identification of risk factors at IBD diagnosis may help healthcare providers to predict EIM in children with IBD and to improve their management for lessening morbidity and enhancing quality of life (QOL),” the authors said.

A retrospective review was conducted on medical records of children with IBD. The authors then recorded EIMs present prior to diagnosis and those detected during follow-up. A total of 100 children (median age, 13.9 years; range, 11.9–15.2) were included.

Of the participants, 46 had EIM, including 10 whose EIM was present before diagnosis and 26 during follow-up. The most common EIM was aphthous stomatitis (18 percent), followed by arthralgia (14 percent), dermatologic manifestations (8 percent), and arthritis (6 percent).

The following risk factors for EIM were identified during follow-up: BMI in the lower or upper quartile (hazard ratio [HR], 9.30 and 23.71, respectively; p<0.001), moderate-to-severe disease activity (HR, 4.43; p<0.001), extensive Crohn’s disease (HR, 3.43; p=0.025), lower haemoglobin level (HR, 2.29; p<0.001), lower albumin level (HR, 2.86; p=0.029), and higher CRP level (HR, 1.04; p<0.001) at diagnosis.

“EIMs are common complications of IBD associated with morbidity and reduced QOL,” the authors said.

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Most Read Articles
06 Jul 2020
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Jairia Dela Cruz, 06 Jul 2020
Following vegan and vegetarian diets, which offer plenty of what is good for health, has been reported to have a downside: an increased risk of depression and anxiety, especially for younger adults.
Pearl Toh, 29 Jun 2020
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
Roshini Claire Anthony, 5 days ago

Upadacitinib may be a suitable treatment for patients with active psoriatic arthritis (PsA) who have insufficient response to non-biologic disease-modifying anti-rheumatic drugs (non-bDMARDs), according to results of the phase III SELECT-PsA-1* trial presented at EULAR 2020.