Most Read Articles
Roshini Claire Anthony, 2 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 5 days ago
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
Jairia Dela Cruz, 6 days ago
Male smokers under the age of 50 years are at risk of developing ischaemic stroke, and this risk increases with the number of cigarettes smoked daily, according to data from the Stroke Prevention in Young Men Study.
Yesterday
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.

BMI, abdominal obesity promote sleep disturbances in postmenopausal women

07 Oct 2017

Both high body mass index (BMI) and abdominal obesity are sources of sleep disturbances in postmenopausal women, negatively affecting deep sleep and sleep efficiency while increasing the risk of obstructive sleep apnoea (OSA), according to a study.

The study included 53 postmenopausal women aged 50 to 70 years from the Ambulatory of Integrative Treatment for Female Sleep Disorders. Of these, 21 were obese (BMI ≥30 kg/m2) and 32 were nonobese (BMI <30 kg/m2). None of the women were receiving hormone therapy.

All participants underwent a full-night polysomnography, with menopause status confirmed by amenorrhea for at least 1 year. Body mass, height, BMI, waist circumference, hip circumference, waist-to-hip ratio (WHR) and neck circumference were also measured.

Results showed that BMI, neck circumference, waist circumference and hip circumference values were significantly greater in the obese vs nonobese group (p<0.01). In contrast, WHR was comparable (p=0.77).

Obese participants specifically had significantly increased values of respiratory disturbance index (16.4 vs 9.3 n[degrees]/h) and apnoea-hypopnea index (14.2 vs 5.6 n[degrees]/h).

Rapid eye movement sleep latency showed a positive correlation with body mass (p<0.01), BMI (p<0.01) and hip circumference (p=0.01). On the other hand, WHR was negatively associated with sleep efficiency (p=0.03).

In a linear regression model, BMI (p<0.01) and WHR (p<0.01) emerged as positive predictors of rapid eye movement sleep latency.

The findings highlight the importance of closely monitoring weight gain and avoiding obesity, especially after menopause, in light of the high prevalence of obesity-related complications that include sleep disorders in postmenopausal women, researchers said.

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Most Read Articles
Roshini Claire Anthony, 2 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 5 days ago
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
Jairia Dela Cruz, 6 days ago
Male smokers under the age of 50 years are at risk of developing ischaemic stroke, and this risk increases with the number of cigarettes smoked daily, according to data from the Stroke Prevention in Young Men Study.
Yesterday
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.